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  1. Ocular inflammatory diseases, including scleritis and uveitis, have been widely treated with immunomodulatory therapies (IMTs) as a steroid-sparing approach. Such strategy includes conventional therapies (anti...

    Authors: Irmak Karaca, Elaine M. Tran, SungWho Park, Albert Bromeo, Hassan Khojasteh, Anh Ngọc Tram Tran, Negin Yavari, Amir Akhavanrezayat, Cigdem Yasar, Gunay Uludag Kirimli, Ngoc Tuong Trong Than, Muhammad Hassan, Christopher Or, Hashem Ghoraba, Diana V. Do and Quan Dong Nguyen
    Citation: Journal of Ophthalmic Inflammation and Infection 2024 14:12
  2. This study aimed to evaluate the clinical correlative factors and outcomes of treatment of bleb-associated endophthalmitis (BAE) following glaucoma filtration surgery in a Chinese population from the year 2012...

    Authors: Liangliang Niu, Yan Luo, Huan Xu, Haili Huang, Rui Jiang and Xinghuai Sun
    Citation: Journal of Ophthalmic Inflammation and Infection 2024 14:11
  3. To describe an unusual case of Whipple’s disease (WD) complicated by uveitis, and subsequent paradoxical worsening after effective antibiotic treatment targeting Tropheryma whipplei (TW).

    Authors: Hippolyte Lequain, Stéphane Abramowicz, Julien Seiller, Amro Abukhashbah, Carole Burillon, Emmanuelle Vignot, Olivier Brunet and Pascal Sève
    Citation: Journal of Ophthalmic Inflammation and Infection 2024 14:10
  4. To report a case of primary vitreoretinal lymphoma masquerading as infectious retinitis that was diagnosed via a retinal biopsy.

    Authors: Nam V. Nguyen, Farid Khan, Andrew Cannon, Ye Huang, Lucas Kim, Rena Xu, Pukhraj Rishi, Christopher D. Conrady, Timothy C. Greiner, Ana Yuil-Valdes and Steven Yeh
    Citation: Journal of Ophthalmic Inflammation and Infection 2024 14:8
  5. Sub-Tenon’s triamcinolone acetonide (STA) is less effective than intravitreal corticosteroids in the treatment of uveitic macular edema (ME), but does have some relative advantages, including substantially low...

    Authors: Amit K. Reddy, Jennifer L. Patnaik and Alan G. Palestine
    Citation: Journal of Ophthalmic Inflammation and Infection 2024 14:7
  6. We report the long-term follow-up of an immunocompetent patient who presented with slowly progressive endogenous endophthalmitis secondary to Streptococcus anginosus. A 46-year-old healthy man presented with a tw...

    Authors: Juan Martin Sanchez, Mauricio Davila, Michael Halpert and Radgonde Amer
    Citation: Journal of Ophthalmic Inflammation and Infection 2024 14:6
  7. This study investigates immune cell (ICs) infiltration in advanced keratoconus patients undergoing autologous adipose-derived adult stem cell (ADASC) therapy with recellularized human donor corneal laminas (CL).

    Authors: Mona El Zarif, Karim Abdul Jawad, Jorge L. Alió, Nehman Makdissy and María P. De Miguel
    Citation: Journal of Ophthalmic Inflammation and Infection 2024 14:5
  8. Capnocytophaga is a bacterium frequently found in the oral flora of dogs and cats (e.g. Capnocytophaga canimorsus) and humans (e.g. Capnocytophaga gingivalis). Among Capnocytophaga related ocular infections, fulm...

    Authors: Lasse Wolfram, David A. Merle, Jonas Neubauer and Spyridon Dimopoulos
    Citation: Journal of Ophthalmic Inflammation and Infection 2024 14:3
  9. Acute posterior multifocal placoid pigment epitheliopathy (APMPPE) is a rare inflammatory eye disorder that is characterized by the presence of multiple placoid lesions in the posterior pole of the eye. Relent...

    Authors: Casper Lund-Andersen, Oliver Niels Klefter and Miklos Schneider
    Citation: Journal of Ophthalmic Inflammation and Infection 2024 14:2
  10. The aim of this report is to describe the risk factors, clinical course, and characteristics of three cases of Paecilomyces keratitis presenting concurrently within three months in the same location. We used in v...

    Authors: Christine K. Kim, Joseph T. Mekhail, David M. Morcos, Christopher D. Yang, Sanjay R. Kedhar, Cinthia Kim, Maria Del Valle Estopinal and Olivia L. Lee
    Citation: Journal of Ophthalmic Inflammation and Infection 2024 14:1
  11. Ring infiltrates usually accompany numerous infectious and sterile ocular disorders. Nevertheless, systemic conditions, drugs toxicity and contact lens wear may present with corneal ring infiltrate in substant...

    Authors: J. Przybek-Skrzypecka, J. Skrzypecki, L. Suh and J. P. Szaflik
    Citation: Journal of Ophthalmic Inflammation and Infection 2023 13:55
  12. To describe a complex case of ocular tuberculosis reactivation with anterior uveitis, choroiditis and inflammatory choroidal neovascular membrane (CNVM) following immune checkpoint inhibitor (ICPI) treatment o...

    Authors: Melissa L. Murphy and Duncan Rogers
    Citation: Journal of Ophthalmic Inflammation and Infection 2023 13:54
  13. There is no consensus concerning restarting anti-tumour necrosis factor (TNF)-α therapy for uveitis after treatment for active tuberculosis (TB). We report a case of Behcet disease (BD) in which treatment with...

    Authors: Chika Toriu, Kinya Tsubota, Yoshihiko Usui and Hiroshi Goto
    Citation: Journal of Ophthalmic Inflammation and Infection 2023 13:52
  14. Unresolved retinal fluid and high injection burden are major challenges for patients with neovascular age-related macular degeneration. Brolucizumab addresses these challenges by providing robust vision gains ...

    Authors: Bahram Bodaghi, Arshad M. Khanani, Ramin Khoramnia, Carlos Pavesio and Quan Dong Nguyen
    Citation: Journal of Ophthalmic Inflammation and Infection 2023 13:51
  15. Viral nucleic acid testing of intraocular fluid using polymerase chain reaction (PCR) is a major laboratory examination in the diagnosis of acute retinal necrosis (ARN). Importantly, false negative PCR results...

    Authors: Haibo Wang, Zhuyun Qian, Lin Cui, Beichen Liu, Jixin Zou, Lu Wang, Yong Tao, Lijun Zhang and Lei Jin
    Citation: Journal of Ophthalmic Inflammation and Infection 2023 13:49
  16. To report the clinical characteristics, antibiotic susceptibilities, and review the literature of Burkholderia cepacia complex (BCC) associated endophthalmitis.

    Authors: Flavius A. Beca, Jesse D. Sengillo, Hailey K. Robles-Holmes, Prashanth G. Iyer, Darlene Miller, Nicolas A. Yannuzzi and Harry W. Flynn
    Citation: Journal of Ophthalmic Inflammation and Infection 2023 13:48
  17. Various organisms, such as bacteria, viruses, and fungi, can cause corneal ulcers. One of the leading causes of vision loss and disability worldwide is corneal ulceration. Practical, accessible, and affordable...

    Authors: Mostafa Feghi, Sharif Makhmalzadeh, Nasrin Masihpour, Mansour Amin and Nader Mortazavinia
    Citation: Journal of Ophthalmic Inflammation and Infection 2023 13:47
  18. Endophthalmitis is among the most sight-threatening infections in ophthalmology practice. Many microorganisms causing endophthalmitis have been reported. Stenotrophomonas maltophilia is among the rare causes of e...

    Authors: Bilge Tarım, Mücella Arıkan Yorgun, Birsen Özdem and Emine Kalkan Akçay
    Citation: Journal of Ophthalmic Inflammation and Infection 2023 13:46
  19. A 47-year-old woman with hypertension and rheumatoid arthritis presented with non-necrotizing scleritis in both eyes. Despite a course of oral corticosteroids, she continued to experience persistent symptoms. ...

    Authors: Anitha Manoharan, Harshita Atmakur, Parthopratim Dutta Majumder and Jyotirmay Biswas
    Citation: Journal of Ophthalmic Inflammation and Infection 2023 13:45
  20. Immunologic and inflammatory adverse effects following vaccination against COVID-19 are being reported. While some reactions may develop denovo others concern its immunogenic effect in patients with pre-existi...

    Authors: Padmamalini Mahendradas, Sai Bhakti Mishra, Rohini Sangoram, Sanjay Srinivasan, Ankush Kawali, Aditya Patil and Rohit Shetty
    Citation: Journal of Ophthalmic Inflammation and Infection 2023 13:44
  21. Dacryoadenitis is an inflammation of the lacrimal gland. This condition has an extensive differential diagnosis, requiring a thorough workup to identify the underlying etiology. If no etiology is identified, t...

    Authors: Samantha D. Butterfield and Rona Z. Silkiss
    Citation: Journal of Ophthalmic Inflammation and Infection 2023 13:43
  22. Uveitic macular edema is a complication of acute or chronic uveitis. Current treatment regiments frequently have numerous side effects, often requiring supplemental treatment. This study investigates the effic...

    Authors: Rishi B. Gupta, Julius Ilin and Chloe C. Gottlieb
    Citation: Journal of Ophthalmic Inflammation and Infection 2023 13:42
  23. Sarcoidosis-associated uveitis, is the predominant ocular sarcoidosis presentation, which affects both adults and children. For adults, international ocular sarcoidosis criteria (IWOS) and sarcoidosis-associat...

    Authors: Magdalena Bazewicz, Jarmila Heissigerova, Carlos Pavesio, François Willermain and Janusz Skrzypecki
    Citation: Journal of Ophthalmic Inflammation and Infection 2023 13:41
  24. This case report describes the course and therapeutic management of a fast-spreading bacterial keratitis caused by multidrug-resistant (MDR) Pseudomonas aeruginosa (P. aeruginosa).

    Authors: Carolin Elhardt, Armin Wolf and Christian Maximilian Wertheimer
    Citation: Journal of Ophthalmic Inflammation and Infection 2023 13:40
  25. Despite HLA-B27-associated uveitis is one of the most frequent etiologies of uveitis worldwide, there are scarce studies on the clinical spectrum of this disease and the implications of therapeutic strategies ...

    Authors: Juan Sebastián Pineda-Sierra, Carlos Cifuentes-González, William Rojas-Carabali, Paula Tatiana Muñoz-Vargas, Alejandro Henao-Posada and Alejandra de-la-Torre
    Citation: Journal of Ophthalmic Inflammation and Infection 2023 13:38
  26. Inflammatory ocular diseases are characterized by the presence of a persistent inflammatory response which cause tissue injury, decrease visual acuity and in severe cases, blindness. Several cytokines represen...

    Authors: Alicia Vázquez, Marisol I. González and José L. Reyes
    Citation: Journal of Ophthalmic Inflammation and Infection 2023 13:37
  27. Multiple evanescent white dot syndrome has been reported to occur following COVID-19 vaccination and also secondary to COVID-19 infection. Increasingly, patients are querying their risk from further vaccinatio...

    Authors: Hannah W. Ng and Rachael L. Niederer
    Citation: Journal of Ophthalmic Inflammation and Infection 2023 13:36
  28. Posterior uveitis is a common chorioretinal pathology affecting all ages worldwide and is a frequent reason for referral to the retina clinic. The spectrum of etiologies for uveitis is very broad and includes ...

    Authors: Manuel Paez-Escamilla, Sonny Caplash, Gagan Kalra, Jamie Odden, Danielle Price, Oscar C. Marroquin, Stephen Koscumb, Patrick Commiskey, Chad Indermill, Jerome Finkelstein, Anna G. Gushchin, Andreea Coca, Thomas R. Friberg, Andrew W. Eller, Denise S. Gallagher, Jean C. Harwick…
    Citation: Journal of Ophthalmic Inflammation and Infection 2023 13:35
  29. To describe unusual clinical features and therapeutic management of a case of cytomegalovirus (CMV) ocular disease in a patient on immunomodulatory therapy.

    Authors: Lorenzo Fabozzi, Ilaria Testi, Laura De Benito-Llopis and Carlos Pavesio
    Citation: Journal of Ophthalmic Inflammation and Infection 2023 13:34
  30. Typical clinical manifestations of ocular toxocariasis are central posterior granuloma, peripheral granuloma and chronic endophthalmitis. Herein we report the presence of peripheral subretinal cysts in two cas...

    Authors: Rym Maamouri, Aida Jallouli, Olfa Béizig and Monia Cheour
    Citation: Journal of Ophthalmic Inflammation and Infection 2023 13:33
  31. The efficacy of tocilizumab in refractory chronic noninfectious uveitis has been previously reported, but no data comparing intravenous and subcutaneous tocilizumab in uveitis are available.

    Authors: Mathilde Leclercq, Paul Goupillou, Hélène Gomez, Marc Muraine, Ygal Benhamou, Nicolas Girszyn and Julie Gueudry
    Citation: Journal of Ophthalmic Inflammation and Infection 2023 13:32
  32. The antimetabolites methotrexate (MTX) and mycophenolate mofetil (MMF) are commonly used as initial corticosteroid-sparing treatment for uveitis. There is little data examining risk factors for failing both MT...

    Authors: Amit K. Reddy, D. Claire Miller, Amol A. Sura, SR Rathinam, John A Gonzales, Radhika Thundikandy, Anuradha Kanakath, Bala Murugan, Rajesh Vedhanayaki, Lyndell L. Lim, Eric B. Suhler, Thuy Doan, Hassan A. Al-Dhibi, Debra A. Goldstein, Lourdes Arellanes-Garcia and Nisha R Acharya
    Citation: Journal of Ophthalmic Inflammation and Infection 2023 13:29
  33. To report a case of combined central retinal vein occlusion (CRVO) with cilioretinal artery occlusion (CLRAO) that heralded the development of frosted branch angiitis (FBA).

    Authors: Abdullah Albahlal, Waleed Khayyat and Sulaiman M. Alsulaiman
    Citation: Journal of Ophthalmic Inflammation and Infection 2023 13:28
  34. Vogt-Koyanagi-Harada (VKH) disease is an idiopathic autoimmune disease which targets melanin-containing tissues such as the uvea, meninges, ear and skin. This typically presents in the eye with acute findings ...

    Authors: Najiha Rahman, Jose Carlo M Artiaga, Konstantinos Bouras, Joshua Luis, Angela Rees and Mark Westcott
    Citation: Journal of Ophthalmic Inflammation and Infection 2023 13:27
  35. Currently, large populations have been vaccinated against COVID-19. The whole inactivated Sinopharm COVID-19 vaccine has been the main available COVID-19 vaccine in Iran. Ocular inflammatory reactions have bee...

    Authors: Mehrdad Motamed Shariati, Mojtaba Abrishami, Shahin Jahani, Ali Bolouki, Mohamad-Reza Ansari-Astaneh and Seyedeh Maryam Hosseini
    Citation: Journal of Ophthalmic Inflammation and Infection 2023 13:26
  36. Epstein-Barr virus is a known cause of dacryoadenitis that is typically sensitive to corticosteroid treatment. When affecting the orbit, particularly the lacrimal gland, Epstein-Barr virus may cause chronic pr...

    Authors: Charissa H. Tan, Pamela S. Tauchi-Nishi and Adam R. Sweeney
    Citation: Journal of Ophthalmic Inflammation and Infection 2023 13:24
  37. Acanthamoeba keratitis is often misdiagnosed at disease onset. This study presents data to confirm the diagnosis using calcofluor white (CFW) staining.

    Authors: Carolin Elhardt, Romina Schweikert, Lennart Maximilian Hartmann, Efstathios Vounotrypidis, Adnan Kilani, Armin Wolf and Christian Maximilian Wertheimer
    Citation: Journal of Ophthalmic Inflammation and Infection 2023 13:23
  38. Interleukin (IL)-6 is an inflammatory cytokine present in the eye during non-infectious uveitis, where it contributes to the progression of inflammation. There are two major IL-6 signaling pathways: classic si...

    Authors: Lisia Barros Ferreira, Liam M. Ashander, Binoy Appukuttan, Yuefang Ma, Keryn A. Williams, Giles Best and Justine R. Smith
    Citation: Journal of Ophthalmic Inflammation and Infection 2023 13:21
  39. This study aimed to investigate the spectrum of ocular characteristics and viral presence in the conjunctival swab of patients with COVID-19.

    Authors: Made Susiyanti, Hisar Daniel, Diah Faridah, Dinda Arken Devona, Pradnya Pramitha, Budiman Bela, Budi Haryanto, Julie Dewi Barliana, Dian Estu, Andi Arus Victor, Nina Dwi Putri, Julius Candra, Nathania Sutandi and Rita S. Sitorus
    Citation: Journal of Ophthalmic Inflammation and Infection 2023 13:20
  40. To evaluate the epidemiologic profile of microbial keratitis in Alexandria- Egypt, with special emphasis on risk factors, visual outcome and microbiological results.

    Authors: Suzan Ibrahim Sakr, Amira Ahmed Nayel, Christeena Saeed Habeel, Hala Kamal Elkhabiry, Ghada Mahmoud Ibrahim, Mona Mohamed Tolba and Alaa Atef Ghaith
    Citation: Journal of Ophthalmic Inflammation and Infection 2023 13:18

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