Articles

Reversible alopecia in Vogt-Koyanagi-Harada disease and sympathetic ophthalmia

Vogt-Koyanagi-Harada (VKH) disease and sympathetic ophthalmia (SO) are both autoimmune disorders targeting melanin-bearing cells, even though their etiologies are different. Both shared many ocular and systemi...

Authors: Chiu-Tung Chuang, Po-Sian Huang, Shih-Chou Chen and Shwu-Jiuan Sheu

Rapid diagnosis of acanthamoeba keratitis using non-nutrient agar with a lawn of E. coli

A patient presented with a corneal foreign body in his only eye. He was treated with prophylactic antibiotics and sent home, but deteriorated.

Authors: Samuel Borin, Ilan Feldman, Shifra Ken-Dror and Daniel Briscoe

Necrotizing scleritis as a complication of cosmetic eye whitening procedure

We report necrotizing scleritis as a serious complication of a cosmetic eye whitening procedure that involves the use of intraoperative and postoperative topical mitomycin C.

Authors: Theresa G Leung, James P Dunn Jr, Esen K Akpek and Jennifer E Thorne

Efficacy of azithromycin 1.5% eye drops in childhood ocular rosacea with phlyctenular blepharokeratoconjunctivitis

The purpose of this study is to report the efficacy of azithromycin 1.5% eye drops in children with ocular rosacea and phlyctenular blepharokeratoconjunctivitis. This retrospective study from January 2009 to M...

Authors: Serge Doan, Eric Gabison, Frédéric Chiambaretta, Melissa Touati and Isabelle Cochereau

A rare case of endogenous Aspergillus conicus endophthalmitis in an immunocompromised patient

The purpose of this study was to report the case of a patient with bilateral panuveitis who was found to have a rarely reported intraocular fungus, Aspergillus conicus. A 40-year-old man presented with gradual vi...

Authors: Wendy M Smith, Gary Fahle, Robert B Nussenblatt and Hatice Nida Sen

Anterior segment optical coherence tomography findings of iris granulomas in Hansen's disease: a case report

A 50-year-old male was diagnosed to have a right eye sclerouveitis and left eye granulomatous anterior uveitis due to Hansen's disease. We are reporting the anterior segment optical coherence tomography (ASOCT...

Authors: Padmamalini Mahendradas, Kavitha Avadhani, Sarika Ramachandran, Sahana Srinivas, Madhavi Naik and K Bhujang Shetty

Chikungunya and the eye: a review

Chikungunya is a self-limited, systemic viral infection that has been a major health problem since the past few years. Ocular manifestations of the disease have become more prevalent in the recent years. Curre...

Authors: Padmamalini Mahendradas, Kavitha Avadhani and Rohit Shetty

Spontaneous closure of macular holes secondary to posterior uveitis: case series and a literature review

The occurrence of a macular hole due to posterior uveitis is infrequently reported. We report the evolution of three cases of macular holes secondary to posterior segment inflammation. A complete inflammatory ...

Authors: Nicolas Bonnin, Pierre-Loïc Cornut, Florian Chaise, Elodie Labeille, Helene Janin Manificat, Audrey Feldman, Laurent Perard, Franck Bacin, Frédéric Chiambaretta and Carole Burillon

Bilateral nongranulomatous anterior uveitis associated with chancre of the tongue: initial presentation of syphilis

This paper reports the case of a pleomorphic manifestation of syphilis, a reemerging sexually transmitted disease.

Authors: Clovis Arcoverde Freitas-Neto, Vinícius Monteiro Castro and Daniel Vitor Vasconcelos-Santos

Ocular tolerability and efficacy of intravitreal and subconjunctival injections of sirolimus in patients with non-infectious uveitis: primary 6-month results of the SAVE Study

The purpose of this study is to evaluate the ocular tolerability and efficacy of sirolimus administered as subconjunctival or intravitreal injections in patients with non-infectious uveitis. Sirolimus as a The...

Authors: Quan Dong Nguyen, Mohamed A Ibrahim, Anthony Watters, Millena Bittencourt, Jithin Yohannan, Yasir J Sepah, James P Dunn, Joel Naor, Naveed Shams, Ovais Shaikh, Henry Alexander Leder and Diana V Do

Endophthalmitis following photorefractive keratectomy with a history of radial keratotomy: a case report

We report the case of an 81-year-old woman with a history of radial keratotomy 9 years prior who developed endophthalmitis without preceding keratitis 4 days after uneventful photorefractive keratectomy surger...

Authors: Peter A Karth and John W Karth

Ultra-wide-field retinal imaging in the management of non-infectious retinal vasculitis

The purpose of this study is to describe and quantify the benefit of ultra-wide-field imaging and fluorescein angiography (FA) in the management of non-infectious retinal vasculitis. In this prospective observ...

Authors: Henry A Leder, John P Campbell, Yasir J Sepah, Theresa Gan, James P Dunn, Elham Hatef, Brian Cho, Mohamed Ibrahim, Millena Bittencourt, Roomasa Channa, Diana V Do and Quan Dong Nguyen

Panretinal acute multifocal placoid pigment epitheliopathy: a novel posterior uveitis syndrome with HLA-A3 and HLA-C7 association

The purpose of this study is to report a previously undescribed clinical entity resembling acute posterior multifocal placoid pigment epitheliopathy (APMPPE) but with an atypical, panretinal and diffuse presen...

Authors: Kevin R Baxter and E Mitchel Opremcak

The emergence of Klebsiella pneumoniae endogenous endophthalmitis in the USA: basic and clinical advances

Endogenous endophthalmitis (EE) is a rare but devastating infection that occurs secondary to seeding of the intraocular cavity from an extraocular focus. Recent reports suggest the increasing prevalence and in...

Authors: Amir H Kashani and Dean Eliott

Simultaneous optic and vestibulocochlear syphilitic neuropathy in a patient with HIV infection

The purpose of this report is to present a case of optic and vestibulocochlear neuropathy as a manifestation of concurrent HIV and syphilis coinfection. This is an interventional case report of a 37-year-old m...

Authors: Ignacio Rodríguez-Uña, Mercedes Serrador-García, Enrique Santos-Bueso, David Díaz-Valle and Julián García-Feijóo

A diagnostic dilemma: infectious versus noninfectious multifocal choroiditis with panuveitis

The objective of this study was to report a diagnostic dilemma in a patient with multifocal choroiditis. This is a case report study.

Authors: Sharel Ongchin, C Dirk Keene, Russell Van Gelder and Gurunadh Atma Vemulakonda

Novel multi-targeted polymerase chain reaction for diagnosis of presumed tubercular uveitis

The objective of this study was to report the use of multi-targeted polymerase chain reaction (PCR) in the diagnosis of presumed tubercular uveitis. Multi-targeted PCR using three targets specific for Mycobacteri...

Authors: Kusum Sharma, Vishali Gupta, Reema Bansal, Aman Sharma, Meera Sharma and Amod Gupta

Repeat corneal graft failure due to graft-to-host herpetic infection

Herein, we present the case of a young female patient with keratoconus, who was subjected twice to repeat keratoplasty, and each time, she experienced a corneal graft failure.

Authors: Zisis Gatzioufas, Andrea Hasenfus, Balasz Gyongyossy, Evangelos Stavridis, Marlies Sauter, Sigrun Smola and Berthold Seitz

A typical bilateral Toxoplasma retinochoroiditis in a bone marrow transplant patient with negative serum titers

Toxoplasma retinochoroiditis can have an atypical presentation and be difficult to diagnose in immunocompromised patients. Accurate diagnosis and appropriate treatment is important since the disease can be aggre...

Authors: Albert Hazan, Rakesh M Patel, David Levinson, Umar Mian and David C Gritz

Conjunctival changes and inflammatory aspects in rabbits' conjunctivas induced by fixed combinations of prostaglandin analogues and timolol maleate

The purpose of this research is to compare the histological and immunohistochemical changes induced by fixed combinations of timolol maleate and prostaglandin analogues in the rabbit conjunctiva. Thirty left e...

Authors: Nubia Vanessa Lima de Faria, Heloisa Helena Russ, Palloma Rose, Lucia Noronha, Paulo Augusto Mello, Fabiano Montiani-Ferreira and Sebastião Cronemberger Sobrinho

Idiopathic retinal vasculitis, arteriolar macroaneurysms and neuroretinitis: clinical course and treatment

The purpose of the study is to describe the clinical course and treatment of idiopathic retinitis, vasculitis, aneurysms and neuroretinitis. The study utilized non-randomized, retrospective and interventional ...

Authors: Alexander Rouvas, Eleni Nikita, Nikos Markomichelakis, Panagiotis Theodossiadis and Nikolaos Pharmakakis

Abiotrophia defectiva causing infectious crystalline keratopathy and corneal ulcer after penetrating keratoplasty: a case report

Infectious crystalline keratopathy is commonly caused by Streptococcus viridans and other gram positive organisms. We present the first case of infectious crystalline keratopathy that developed into a corneal ulc...

Authors: Yannis M Paulus and Glenn C Cockerham

High definition spectral domain optical coherence tomography of retinal pigment epithelial rip in a case of sympathetic ophthalmia

We are reporting a case of granulomatous panuveitis in the right eye following penetrating injury to the left eye.

Authors: Padmamalini Mahendradas, Kavitha Avadhani, Bhanumathi Madhavarao, Anand Vinekar, Kodandaramaiah Sahana, Rohit Shetty and Bhujang K Shetty

Successful treatment of corneal wasp sting-induced panuveitis with vitrectomy

This study aims to present the management and clinical findings of a case of corneal wasp sting and to report the outcome of corneal change and panuveitis after vitrectomy.

Authors: Yusuke Nakatani, Akira Nishimura and Kazuhisa Sugiyama

Retinal arteriolar occlusions due to cytomegalovirus retinitis in elderly patients without HIV

Five of 7 (71%) elderly immunocompetent patients with cytomegalovirus retinitis had retinal arteriolar occlusions versus 2 of 8 (25%) elderly immunocompromised patients and 1 of 19 (5%) younger HIV-infected pa...

Authors: Janet L Davis, Payman Haft and Kristen Hartley

Branch retinal artery occlusion associated with posterior uveitis

The purpose of this study is to report the clinical features and visual outcome of branch retinal artery occlusion (BRAO) associated with posterior uveitis. This is a retrospective study including the 18 eyes ...

Authors: Rim Kahloun, Samah Mbarek, Imen Khairallah-Ksiaa, Bechir Jelliti, Salim Ben Yahia and Moncef Khairallah

Bilateral ischemic maculopathy in acquired immune deficiency syndrome

This brief report aims to report a case of bilateral macular ischemia as a cause of sudden decreased vision in a patient with acquired immune deficiency syndrome (AIDS).

Authors: Kiran Turaka, Rahul Reddy, Ashkahn Golshani, Wong Yu Khaw and J Shepard Bryan

Associations of Fuchs heterochromic iridocyclitis in a South Indian patient population

The purpose of this study is to look for any possible associations in 58 consecutive cases of Fuchs heterochromic iridocyclitis (FHI) in a South Indian patient population. Fifty-eight consecutive cases (59 eye...

Authors: Kalpana Babu, Madhura Adiga, Sunil R Govekar, BV Ravi Kumar and Krishna R Murthy

Peripapillary choroidal neovascularization in pars planitis

Choroidal neovascularization (CNV) is a rare complication of intermediate uveitis. Risk factors are not well-characterized. Here, we describe a case of peripapillary CNV in a patient with intermediate uveitis ...

Authors: Sonia Mehta, Luxme Hariharan, Allen C Ho and John H Kempen

OX40 ligand expression abrogates the immunosuppressive function of retinal pigment epithelium

This study aims to investigate the role of OX40 ligand (OX40L) in ocular inflammation via abrogation of retinal pigment epithelium (RPE)-mediated immunosuppression using an in vitro expression approach. OX40L cDN...

Authors: Matthew A Cunningham, Zhuqing Li, Baoying Liu, Steven Yeh and Robert B Nussenblatt

Eales' disease - current concepts in diagnosis and management

Eales' disease, first described by the British ophthalmologist Henry Eales in 1880, is characterized by three overlapping stages of venous inflammation (vasculitis), occlusion, and retinal neovascularization. ...

Authors: Jyotirmay Biswas, Reesha Karingattil Ravi, Angayarkanni Naryanasamy, Lily Therese Kulandai and Hajib Naraharirao Madhavan

Moxifloxacin and bilateral acute iris transillumination

Recent publications have alerted clinicians to a syndrome of uveitic transilluminating iris depigmentation associated with systemic fluoroquinolones and other antibiotics. Bilateral acute iris transilluminatio...

Authors: Robert M Knape, Fouad E Sayyad and Janet L Davis

Perspectives of Quantiferon TB Gold test among Indian practitioners: a survey

The aim of this study is to determine the preferences and perspectives regarding the Quantiferon TB Gold test for the diagnosis of tuberculosis (TB) in India. A survey was distributed among 46 uveitis speciali...

Authors: Kalpana Babu, Mariamma Philips and Doddaballapur Krishnaswamy Subbakrishna

Statin use and ocular inflammatory disease risk

This study aims to evaluate the effect of oral statin medication use on the subsequent development of ocular inflammatory disease (OID). A retrospective nested case–control study was carried out on patient rec...

Authors: Jacob J Yunker, Gerald McGwin Jr and Russell W Read

Subconjunctival dexamethasone implant for non-necrotizing scleritis

The purpose of this study is to report the management of non-necrotizing anterior scleritis with a single-dose subconjunctival 0.7 mg dexamethasone implant (Ozurdex®, Allergan, Inc., CA, USA). Six patients wit...

Authors: Heloisa Nascimento, Maíra França, Luciana Guadalupe García, Cristina Muccioli and Rubens Belfort Jr

Polymicrobial endophthalmitis: prevalence, causative organisms, and visual outcomes

The purpose of the present study is to evaluate the prevalence, causative organisms, and visual acuity outcome in patients with culture-proven polymicrobial endophthalmitis. The method used in this study is th...

Authors: Animesh Jindal, Mayur R Moreker, Avinash Pathengay, Manav Khera, Subhadra Jalali, Ajit Majji, Annie Mathai, Savitri Sharma, Taraprasad Das and Harry W Flynn Jr

Retinal vasculitis in Toxocara canis neuroretinitis

The purpose of this case report is to describe clinical and angiographic findings of retinal vasculitis in acute Toxocara canis neuroretinitis associated with systemic infection.

Authors: Cagri G Besirli and Susan G Elner

Use of linseed oil to treat experimentally induced keratoconjunctivitis sicca in rabbits

The objective of this study was to evaluate the effectiveness of various linseed oil (LO) preparations (oral, topical, oral and topical combined) in treating experimentally induced keratoconjunctivitis sicca (...

Authors: Magda Luzia Neves, Letícia Yamasaki, Osimar de Carvalho Sanches, Marcelo Sávio Paiva do Amaral, Helaine Stevanin, Rogério Giuffrida, Eudes Ramalho Candido, Jonatas Eduardo Góes, Luís Felipe da Costa Zulim, Augusto Schweigert, Rosimery Missuzu Fukui, Carlos Collares Meirelles, Carolina Akemi Sasaki and Silvia Franco Andrade

Isolated cortical blindness without simultaneous neurological involvement in progressive multifocal leukoencephalopathy in a patient with human immune deficiency virus infection

This is a case report of cortical blindness in a HIV-positive patient with progressive multifocal leukoencephalopathy (PML) without any other associated neurological dysfunction.

Authors: Vijay Ananth Jeyaraman, Sridharan Sudharshan, Ambika Selvakumar, Shika Bassi, Olma Veena Noronha, Poongulali Selvamuthu, Nagalingeshwaran Kumarasamy and Jyotirmay Biswas

Ocular lesions in 1,000 consecutive HIV-positive patients in India: a long-term study

Ocular lesions in patients on highly active antiretroviral therapy (HAART) have shown changes in disease prevalence and pattern. Although they have been described in the Western population, there are not many ...

Authors: Sridharan Sudharshan, Sheikh Kaleemunnisha, Akbar Ashraf Banu, Sankaran Shrikrishna, Amala E George, B Rajesh Babu, Bella Devaleenal, Nagalingeshwaran Kumarasamy and Jyotirmay Biswas

Prevalence of presumed ocular tuberculosis among pulmonary tuberculosis patients in a tertiary hospital in the Philippines

The objective of this study was to determine the prevalence of presumed ocular tuberculosis among diagnosed pulmonary tuberculosis patients in a tertiary government hospital in the Philippines and determine it...

Authors: Leon Paolo R Lara and Vicente Ocampo Jr

Retinal vasculitis associated with pyoderma gangrenosum: a case report

Authors: Nilay Yuksel and Sengul Ozdek

Indocyanine green angiography findings in patients with nonfamilial amyloidosis

The purpose of this study is to assess indocyanine green angiographic findings in patients with nonfamilial amyloidosis.

Authors: Sonia Attia, Rim Kahloun, Sameh Mbarek, Olfa Harazallah, Habib Skhiri, Salim Ben Yahia and Moncef Khairallah

Probable Vogt–Koyanagi–Harada disease with initial unilateral ocular manifestation in a hepatitis C carrier

Authors: Nikki Y. Far and David T. L. Liu

Golimumab for the treatment of refractory juvenile idiopathic arthritis-associated uveitis

Authors: Mridula William, Sepideh Faez, George N. Papaliodis and Ann-Marie Lobo

A case of subconjunctival dirofilariasis in South India

We describe a case of subconjunctival dirofilariasis from South India. The worm was identified by detailed morphologic study.

Authors: Savita Bhat, Ovi Sofia, M. Raman and Jyotirmay Biswas

A case report of cryptococcal meningoencephalitis presenting as uveitis

Authors: Nikita Abhyankar, Showrob Patwary, Swathi Panneerselvam, Nirodhini Narendran and Yit C. Yang

Immunohistochemical study of epiretinal membranes in patients with uveitis

The purpose of this study is to report two cases of idiopathic uveitis with secondary epiretinal membrane (ERM) formation in order to describe histologic and immunohistochemical features that may help distingu...

Authors: Arsham Sheybani, George J. Harocopos and P. Kumar Rao

Retinal optical coherence tomography manifestations of intraocular lymphoma

Primary central nervous system lymphoma (PCNSL) is a rare disease. The index report describes a patient with intraocular lymphoma secondary to recurrent PCNSL and corresponding retinal findings on spectral dom...

Authors: Tin Yan Alvin Liu, Mohamed Ibrahim, Millena Bittencourt, Yasir J. Sepah, Diana V. Do and Quan Dong Nguyen

Bilateral scleritis and sclerokeratitis associated with IgA nephropathy

The purpose of this study is to report a case of bilateral nodular scleritis in a patient with final diagnosis of IgA nephropathy.

Authors: Manuel Garza-Leon, Diana Flores, Gabriela Alarcón-Galván and Concepción Sánchez-Martínez