Fig. 1

Multimodal imaging of Whipple’s disease uveitis at presentation. A Fundus photograph of the right eye revealing minimal vitreous haze associated with severe optic nerve head edema, and mild whitish retinal changes in the temporal macula. B Fundus photograph of the left eye at presentation revealing moderate vitreous haze associated with optic nerve head edema with very hazy details. C Fluorescein angiography (FA) of the right eye showing profuse optic disc leakage, extensive capillary leakage over the entire posterior pole, and an associated area of venous vasculitis at the level of the superotemporal arcade. D FA of the left eye showing moderate optic disc leakage, capillary leakage, and superotemporal venous vasculitis. A small punctiform hyperfluorescent focus can be seen above the disc. E Macular spectral-domain optical coherence tomography (SD-OCT) of the right eye demonstrating a mild epiretinal membrane (ERM), diffuse macular thickening without cystic changes, and some discrete intraretinal hyperreflective dots (arrows). F Macular SD-OCT of the left eye demonstrating a mild ERM, diffuse macular thickening with one intraretinal cystic cavity (arrowhead), and some discrete intraretinal hyperreflective dots. G Optic nerve head SD-OCT of the right eye showing severe disc edema, mainly secondary to retinal nerve fiber layer (RNFL) edema