Fig. 4
From: Diagnosis of primary vitreoretinal lymphoma masquerading infectious retinitis by retinal biopsy
Histologic examination of retinal biopsies demonstrated near complete effacement of retinal architecture by large, atypical lymphocytes (A, B). These atypical cells were CD20-positive (C) while CD3-stained cells were reactive with small, background T-lymphocytes (D). The atypical cells were CD10-negative (E), 60%-70% of cells stain for BCL6 (F) and greater than 80% of cells were reactive with MUM1 (3G). Ki67-stained cells were markedly elevated (H). (BCL-6: B-cell lymphoma 6; MUM1: multiple myeloma oncogene-1; Ki67: Antigen Kiel 67)