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Table 1 Characteristics of treatment successes and double treatment failures

From: Risk of failing both methotrexate and mycophenolate mofetil from the First-line Antimetabolites as Steroid-sparing Treatment (FAST) uveitis trial

Baseline characteristic

Success (N=115)

Double Failure (N=22)

All (N=137)

P-value

Sex

ā€ƒFemale

76 (66%)

16 (73%)

92 (67%)

0.72

ā€ƒMale

39 (34%)

6 (27%)

45 (33%)

Ā 

Age (years)

ā€ƒMean (SD)

41 (15)

35 (17)

40 (15)

0.14

ā€ƒMedian (Q1, Q3)

39 (30, 53)

29 (23, 46)

37 (26, 53)

Ā 

Laterality

ā€ƒUnilateral

10 (8.7%)

3 (14%)

13 (9.5%)

0.44

ā€ƒBilateral

105 (91%)

19 (86%)

124 (91%)

Ā 

Anatomic location

ā€ƒAnterior/Intermediate

18 (26%)

10 (46%)

28 (20%)

0.003

ā€ƒPosterior/Panuveitis

97 (74%)

12 (55%)

109 (80%)

Ā 

CME

ā€ƒNo

85 (74%)

10 (46%)

95 (69%)

0.016

ā€ƒYes

30 (26%)

12 (55%)

42 (31%)

Ā 

Retinal vasculitis

ā€ƒNo

58 (50%)

4 (18%)

62 (45%)

0.006

ā€ƒYes

9 (7.8%)

5 (23%)

14 (10%)

Ā 

ā€ƒFA not done

48 (42%)

13 (59%)

61 (45%)

Ā 

Uveitis durationĀ (months)

ā€ƒMean (SD)

25 (52)

31 (52)

26 (52)

0.63

ā€ƒMedian (Q1, Q3)

3.2 (0.63, 25)

7.9 (3.5, 27)

3.8 (0.64, 26)

Ā 

ā€ƒMissing

1 (0.9%)

1 (4.5%)

2 (1.5%)

Ā 

Country

ā€ƒAustralia

8 (7.0%)

4 (18%)

12 (8.8%)

0.18

ā€ƒIndia

77 (67%)

12 (55%)

89 (65%)

Ā 

ā€ƒSaudi Arabia

7 (6.1%)

0 (0%)

7 (5.1%)

Ā 

ā€ƒUS/Mexico

23 (20%)

6 (27%)

29 (21%)

Ā 

Study site

ā€ƒCoimbatore

21 (18%)

4 (18%)

25 (18%)

0.18

ā€ƒMadurai

35 (30%)

6 (27%)

41 (30%)

Ā 

ā€ƒMelbourne

8 (7.0%)

4 (18%)

12 (8.8%)

Ā 

ā€ƒMexico

1 (0.9%)

0 (0%)

1 (0.7%)

Ā 

ā€ƒPondicherry

21 (18%)

2 (9.1%)

23 (17%)

Ā 

ā€ƒPortland

5 (4.3%)

4 (18%)

9 (6.6%)

Ā 

ā€ƒRiyadh

7 (6.1%)

0 (0%)

7 (5.1%)

Ā 

ā€ƒSan Francisco

17 (15%)

2 (9.1%)

19 (14%)

Ā