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Table 3 Multivariate analysis of risk factors for secondary glaucoma in eyes with VKH disease

From: Risk factors for secondary Glaucoma in patients with Vogt-Koyanagi-Harada disease

Risk Factor

Non-glaucoma (n = 78)a

Glaucoma (n = 16)b

Relative Risk (95% CI)

p Valuec

Oral prednisone > 24 months

24 (30.8)

12 (85.7)

9.33 (2.21–39.28)

< 0.001

Topical steroids > 12 months

26 (33.3)

10 (71.4)

3.88 (1.31–11.46)

0.007

Anterior chamber cells ≥2+

37 (47.4)

11 (78.6)

3.36 (1.003–11.26)

0.032

≥2 recurrences

26 (33.3)

12 (85.7)

8.52 (2.02–35.92)

< 0.001

Chronic-recurrent stage

13 (16.7)

6 (42.9)

2.88 (1.11–12.63)

0.037

Angle-closure

14 (18.9)

10 (71.4)

7.08 (2.44–20.48)

< 0.001

Iris bombé

6 (7.7)

6 (42.9)

5.00 (2.10–11.90)

0.002

Peripapillary atrophy

10 (12.8)

6 (42.9)

3.56 (1.43–8.85)

0.014

  1. VKH Vogt-Koyanagi-Harada
  2. aTwo eyes without management with oral prednisone (convalescent stage) were excluded
  3. bFour eyes with glaucoma at first visit were excluded
  4. cp-value > 0.05 is considered statistically significant