From: Risk factors for secondary Glaucoma in patients with Vogt-Koyanagi-Harada disease
Baseline characteristics | Non-glaucoma (n = 80 eyes, %) | Glaucoma (n = 20 eyes, %) | p Valued |
---|---|---|---|
Female gender | 68 (85.0) | 20 (100.0) | 0.327 |
Age (years)a | 35 (26.7–45.7) | 37 (29–54) | 0.304 |
Extraocular findingsb | |||
Poliosis | 2 (5.0) | 2 (20.0) | 0.049 |
Vitiligo | 4 (10.0) | 3 (30.0) | 0.021 |
Flu-like | 14 (35.0) | 4 (40.0) | 0.600 |
Headache | 30 (75.0) | 8 (80.0) | 0.640 |
Tinnitus | 25 (62.5) | 5 (50.0) | 0.307 |
VKH stage at presentation | |||
Uveitic | 62 (77.5) | 7 (35.0) | < 0.001 |
Chronic-recurrent | 14 (17.5) | 13 (65.0) | < 0.001 |
Convalescent | 4 (5.0) | 0 (0) | < 0.001 |
Angle configuration | |||
Open | 64 (80.0) | 5 (25.0) | < 0.001 |
Closed | 16 (20.0) | 15 (75.0) | < 0.001 |
Outcomes at last visit | |||
BCVA (LogMAR)a | 0.2 (0–0.6) | 0.55 (0.22–2.3) | 0.003 |
VKH signs (n = 98)b | |||
Sunset glow fundus | 50 (62.5) | 16 (88.9)c | 0.031 |
Dalen-Fuchs nodules | 58 (60) | 18 (100)c | 0.001 |
Serous retinal detachment | 2 (2.5) | 1 (5.6)c | 0.460 |
Peripapillary atrophy | 39 (37.5) | 14 (77.8)c | 0.002 |
Papillitis | 2 (2.5) | 0 (0) | < 0.001 |
C/D ratio (n = 35)ad | 0.4 (0.3–0.4) | 0.8 (0.55–0.9) | < 0.001 |
Recurrence (yes) | 44 (55.0) | 15 (75.0) | 0.130 |
Time to achieve inflammatory control (months)a | 2 (1–3) | 3 (2–3) | 0.026 |
Time to first recurrence (months)a | 5 (2–8) | 18 (8–48) | < 0.001 |
Exposure topical steroids (months)a | 8.5 (2.2–24) | 25 (14–54) | 0.008 |
Exposure oral prednisone (months)a | 11.5 (7–26.7) | 62 (39–104) | < 0.001 |