Table 2 Diagnostic criteria for initial-onset acute Vogt-Koyanagi-Harada disease^a

1.

No ocular trauma or surgery preceding onset of disease^b

2.

Bilateral involvement (verified with ICGA and/or EDI-OCT)^b

3.

Exclusion of other infectious, inflammatory or masquerading entities, in particular other stromal choroiditis entities (i.e., tuberculosis, sarcoidosis or syphilis)^b

4.

Diffuse choroiditis evidenced by ICGA and/or EDI-OCT^b

5.

Signs and symptoms of less than 4 weeks’ duration^b

6.

Absence of clinical findings compatible with chronic disease (i.e. sunset glow fundus or integumentary signs (vitiligo, alopecia & poliosis)^b

7.

Exudative retinal detachments (evidenced by pooling and pinpoint leaking points on FA and ICGA) (very helpful criterion when present)

8.

Disc hyperfluorescence (helpful criterion).

9.

Neurological / auditory findings (meningismus, tinnitus, acute hearing loss) (helpful criterion).