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Table 2 In vitro antibiotic susceptibility profiles of Nocardia keratitis isolates

From: Nocardia keratitis: amikacin nonsusceptibility, risk factors, and treatment outcomes

Nocardia Species number of isolates Amikacin Tobramycin Ciprofloxacin Moxifloxacin Clarithromycin Doxycycline Minocycline Trimethoprim-Sulfa Linezolid Imipenem Amoxicillin-Clavulanic Acid Ceftriaxone Cefepime
Nocardia amikacinitolerans 11 0% 82% 0% 9% 0% 36% 100% 100% 100% 18% 100% 27% 0%
Nocardia beijingensis 3 33% 100% 0% 0% 0% 33% 100% 100% 100% 0% 100% 67% 67%
Nocardia arthritidis 2 100% 50% 33% 50% 50% 50% 50% 100% 100% 0% 50% 50% 50%
Nocardia harenae 1 100% 100% 100% 100% 100% 100% 100% 100% 100% 100% 100% 100% 100%
Nocardia farcinica 1 100% 0% 0% 100% 0% 0% 0% 100% 100% 100% 100% 0% 0%
Nocardia veterana 1 100% 0% 0% 0% 100% 0% 0% 100% 100% 100% 0% 0% 100%
N. asteroides complex 1 0% 100% 0% 0% 0% 0% 0% 100% 100% 0% 0% 0% 0%
N. endophytica 1 100% 100% 100% 100% 100% 100% 100% 100% 100% 0% 0% 100% 100%
Nocardia bhagyanarayanae 1 100% 100% 0% 0% 0% 0% 100% 100% 100% 0% 100% 0% 100%
Nocardia testacea 1 0% 100% 0% 0% 100% 100% 100% 100% 100% 0% 100% 100% 0%
N. beijingensis/pneumoniae 1 100% 100% 100% 100% 0% 0% 100% 100% 100% 100% 0% 100% 100%
Nocardia beijingensis/pneumoiae/avagensis 1 0% 100% 0% 0% 0% 0% 0% 100% 100% 100% 100% 100% 0%
% Susceptible   36% 80% 16% 24% 20% 36% 80% 100% 100% 28% 80% 44% 32%
% Resistant 64% 12% 80% 60% 80% 8% 0% 0% 0% 44% 12% 24% 60%
% Intermediate 0% 8% 4% 16% 0% 56% 20% 0% 0% 28% 8% 32% 8%
MIC50 (ug/ml) < 32 (R) < 1 (S) > 4 (R) > 4 (R) > 16 (R) < 2 (I) < 1 (S) < 0.5 (S) < 2 (S) > 8 (R) < 4 (S) 16 (I) > 32 (R)
MIC90 (ug/ml) > 64 (R) > 12.8(R) > 4 (R) > 8 (R) > 16 (R) > 6.4(R) 3.2 (I) 3.9 (S) 3.2 (S) > 51.2(R) > 25.6(R) > 64 (R > 32 (R)