Skip to main content

Table 1 Patient characteristics

From: The acute phase response protein SERPINA3 is increased in tear fluid from the unaffected eyes of patients with unilateral acute anterior uveitis

 

Healthy control

Acute anterior uveitis

Bacterial keratitis

P-value

N

14

13

7

Age (years)

41.1 ± 11.6

40.1 ± 16.2

40.2 ± 15.3

0.98a

Female/male

9/5

8/5

5/2

0.91b

Ethnicity (Caucasian/Asian/Hispanic/African)

13/1/0/0

11/1/1/0

5/0/1/1

0.38b

Duration of symptoms prior to tear fluid sampling (days)

N/A

4.8 ± 3.6

2.4 ± 1.5

0.13c

IOP in affected eye (mmHg)

14.3 ± 3.0*

10.7 ± 2.4

12.8 ± 3.2

0.008d

IOP in unaffected eye (mmHg)

14.3 ± 3.0*

13.8 ± 3.1

12.0 ± 2.5

0.28a

Schirmer’s test in affected eye (mm)

13.4 ± 8.8*

27.0 ± 12.0

16.3 ± 11.0

0.019e

Schirmer’s test in unaffected eye (mm)

13.4 ± 8.8*

10.8 ± 9.8

7.7 ± 1.2

0.25f

Laser flare meter in affected eye (ph/ms)

4.5 ± 1.1*

170.5 ± 175.7

45.5 ± 64.7

< 0.001e

Laser flare meter in unaffected eye (ph/ms)

4.5 ± 1.1*

4.4 ± 2.8

4.6 ± 1.3

0.98a

HLA-B27 positive (number of patients)

4g

 

Bacteria identified in microbial culture (number of patients)

6h

 
  1. IOP Intraocular pressure, *Average of both eyes in healthy control; a One-way analysis of variance (ANOVA); b Chi-square; c Mann-Whitney U test; d ANOVA followed by Tukey’s post hoc test between patients with acute anterior uveitis and healthy control; e Kruskal-Wallis H test followed by pairwise Mann-Whitney U test between patients with acute anterior uveitis and healthy control; f Kruskal-Wallis H test; g one patient with ankylosing spondylitis, one patient with reactive arthritis; h S.aureus, S.epidermidis and P.acnes