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Table 1 Patient characteristics

From: The acute phase response protein SERPINA3 is increased in tear fluid from the unaffected eyes of patients with unilateral acute anterior uveitis

  Healthy control Acute anterior uveitis Bacterial keratitis P-value
N 14 13 7
Age (years) 41.1 ± 11.6 40.1 ± 16.2 40.2 ± 15.3 0.98a
Female/male 9/5 8/5 5/2 0.91b
Ethnicity (Caucasian/Asian/Hispanic/African) 13/1/0/0 11/1/1/0 5/0/1/1 0.38b
Duration of symptoms prior to tear fluid sampling (days) N/A 4.8 ± 3.6 2.4 ± 1.5 0.13c
IOP in affected eye (mmHg) 14.3 ± 3.0* 10.7 ± 2.4 12.8 ± 3.2 0.008d
IOP in unaffected eye (mmHg) 14.3 ± 3.0* 13.8 ± 3.1 12.0 ± 2.5 0.28a
Schirmer’s test in affected eye (mm) 13.4 ± 8.8* 27.0 ± 12.0 16.3 ± 11.0 0.019e
Schirmer’s test in unaffected eye (mm) 13.4 ± 8.8* 10.8 ± 9.8 7.7 ± 1.2 0.25f
Laser flare meter in affected eye (ph/ms) 4.5 ± 1.1* 170.5 ± 175.7 45.5 ± 64.7 < 0.001e
Laser flare meter in unaffected eye (ph/ms) 4.5 ± 1.1* 4.4 ± 2.8 4.6 ± 1.3 0.98a
HLA-B27 positive (number of patients) 4g  
Bacteria identified in microbial culture (number of patients) 6h  
  1. IOP Intraocular pressure, *Average of both eyes in healthy control; a One-way analysis of variance (ANOVA); b Chi-square; c Mann-Whitney U test; d ANOVA followed by Tukey’s post hoc test between patients with acute anterior uveitis and healthy control; e Kruskal-Wallis H test followed by pairwise Mann-Whitney U test between patients with acute anterior uveitis and healthy control; f Kruskal-Wallis H test; g one patient with ankylosing spondylitis, one patient with reactive arthritis; h S.aureus, S.epidermidis and P.acnes