Table 4 Top upstream regulators
Patient 1 | Patient 2 | Patient 3 | Patient 4 | Patient 5 | |||||
|---|---|---|---|---|---|---|---|---|---|
Protein | P value | Protein | P value | Protein | P value | Protein | P value | Protein | P value |
MAPT | 1.32E−24 | APP | 5.03E−11 | MAPT | 7.78E−15 | IL6 | 1.65E−16 | MAPT | 5.83E−12 |
APP | 1.78E−22 | MAPT | 5.49E−11 | APP | 6.79E−13 | APP | 1.46E−14 | APP | 1.72E−11 |
TP53 | 3.21E−19 | PSEN1 | 2.71E−09 | TNF | 8.03E−13 | MAPT | 2.12E−13 | ZNF106 | 3.96E−11 |
TNF | 9.00E−19 | Growth hormone | 2.87E−07 | PSEN1 | 3.75E−12 | PCGEM1 | 4.90E−12 | PSEN1 | 6.04E−10 |
PSEN1 | 1.40E−17 | MYC | 7.50E−07 | IL6 | 1.04E−11 | TNF | 5.37E−11 | IL6 | 9.72E−10 |