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Table 3 Characteristics of fundus photography and fundus autofluorescence for all 13 patients with npAIR

From: Non-paraneoplastic autoimmune retinopathy: multimodal testing characteristics of 13 cases

Patient Affected eye Fundus photography FAF
1 OU Normal OU Not done
2 OS Optic nerve head pallor, attenuated vessels, RPE mottling, bone spicule-like pigment patches Not done
3 OS Small area of altered pigment at 2 o’clock superior and temporal to the optic nerve Hyperautofluorescence surrounding the optic nerve and macula with normal autofluorescence inside of the ring
4 OU Mild optic nerve head pallor, attenuated vessels, RPE mottling in mid-periphery OU Not done
5 OU Mild pigmentary change surrounding a few drusen in mid-periphery OU Not done
6 OD Mildly attenuated retinal vessels Not done
7 OS Normal Normal
8 OS Attenuated vessels, scattered RPE changes Perivascular stippled hypoautofluorescence
9 OU Diffuse atrophy of RPE, RPE mottling in the macula Normal OD, peripapillary area hypoautofluorescence OS
10 OS Mild optic nerve head pallor, attenuated vessels, scattered RPE changes Diffuse hyperautofluorescence posterior pole extending from the macula around the arcades and optic nerve
11 OD Normal Hyperautofluorescence around the optic nerve and macula
12 OD Bone spicules, rare anterior vitreous cells Hyperautofluorescence surrounding the macula with normal autofluorescence inside the ring, speckled hypoautofluorescence superior, nasal, and inferior to the optic nerve
13 OU Central atrophy of the RPE, optic nerve head pallor OU Macular hypoautofluorescence OU with slight hyperautofluorescence speckled in posterior pole