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Journal of Ophthalmic Inflammation and Infection

Table 1 Pharmacokinetic parameters of difluprednate in the aqueous humor, cornea and conjunctiva after a single instillation

From: Bioavailability of generic 0.05% difluprednate emulsion in the aqueous humor, cornea, and conjunctiva of New Zealand rabbits after a single dose compared with commercial difluprednate

PK parameter

Aqueous humor

Cornea

Conjunctiva

Generic

Commercial

Generic

Commercial

Generic

Commercial

Tmax

30

30

15

15

60

60

Cmax

35

27

1072

1255

25,288

31,351

T1/2

2.1

2.1

1.1

1.4

4.6

4.2

  1. Concentration in nanograms per milliliter
  2. T max time of maximum concentration, C max maximum concentration, T 1/2 half-life
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