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Table 3 Multimodal imaging features of alterations observed on optical coherence tomography angiography in patients with acute Vogt-Koyanagi-Harada syndrome and acute central serous chorioretinopathy

From: Distinguishing features of acute Vogt-Koyanagi-Harada disease and acute central serous chorioretinopathy on optical coherence tomography angiography and en face optical coherence tomography imaging

Feature

Condition

Appearance of choriocapillaris on OCTA

Associated retinal/pigment epithelial/choroidal features

Features on EDI-OCT and/or ICGA

Dense dark areas

CSC

Single well-defined uniformly hyporeflective areas of apparent flow void

PED

Hyper-reflective dome-shaped elevation of the RPE on EDI-OCT

Mottled dark areas

CSC

Irregular, areas of mixed hypo- and hyper-reflectance with ill-defined margins

SSRD

Homogenous hyporeflective space between the neurosensory retina and RPE on EDI-OCT

Multifocal dark spots

VKH

Multiple, round-to-oval, well-defined, variably sized hyporeflective areas suggestive of choriocapillaris flow void

Choroidal inflammatory foci

Choriocapillaris ischemia on ICGA