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Table 1 Aspects of four patients with syphilitic uveitis presenting with retinal detachment and fulminant fibroglial proliferation

From: Fulminant proliferative vitreoretinopathy in syphilitic uveitis

Case

Initial BCVA

Laboratory results

Presentation of posterior uveitis

Duration of treatment

Outcome after treatmenta

Final BCVA

Case 1

OD: 20/63

Serum: + VDRL: 1/512 + TPHA

OD: PRI

Intravenous penicillin: 14 days

OD: Macular pucker (21 weeks)

OD: 20/63

OS: HM

CSF: + VDRL

Pleocytosis

HIV: negative

OS: PRI, NRC

Prednisone: 60 mg/day (tapering regimen for 7 weeks)

OS: Tractional RD (8 weeks)

OS: CF

Case 2

OD: HM

Serum: + VDRL: 1/1024 + TPHA

OD: NRC

Intravenous penicillin: 21 days

OD: Mixed RD (2 weeks)

OD: LP

OS: HM

CSF: + VDRL

Pleocytosis

HIV: positive

OS: NRC

Prednisone: 60 mg/day (tapering regimen for 7 weeks)

OS: Mixed RD (1 week)

OS: 20/150

Case 3

OD: CF

Serum: + VDRL:1/4096 + THPA

OD: NRC

Intravenous penicillin: 21 days

OD: Macular Pucker (5 weeks)

OD: 20/250

OS: HM

CSF: + VDRL

Pleocytosis

HIV: negative

OS: PPCR, PRI, NRC

Prednisone: 60 mg/day (tapering regimen for 10 weeks)

OS: Mixed RD (4 weeks)

OS: HM

Case 4

OD: HM

Serum: + VDRL: 1/512 + THPA

OD: NRC

Intravenous penicillin: 21 days

OD: Tractional RD (2 weeks)

OD: NLP

OS: 20/200

CSF: − VDRL

HIV: positive

OS: Optic disc hyperemia, vascular sheathing

Prednisone: 60 mg/day (tapering regimen for 4 weeks)

OS: No lesions

OS: 20/20

  1. BCVA best corrected visual acuity, OD right eye, OS left eye, HM hand movements, VDRL Venereal Disease Research Laboratory, TPHA Treponema pallidum hemagglutination assay, CSF cerebrospinal fluid, HIV human immunodeficiency virus, PRI punctate inner retinal infiltrates, NRC necrotizing retinochoroiditis, RD retinal detachment CF, counting fingers, LP light perception PPCR, posterior placoid chorioretinitis, NPL no light perception
  2. aThe time indicated in brackets refers to interval between initial diagnosis and moment that the complication occurred / was detected.