Skip to main content

Table 1 Aspects of four patients with syphilitic uveitis presenting with retinal detachment and fulminant fibroglial proliferation

From: Fulminant proliferative vitreoretinopathy in syphilitic uveitis

Case Initial BCVA Laboratory results Presentation of posterior uveitis Duration of treatment Outcome after treatmenta Final BCVA
Case 1 OD: 20/63 Serum: + VDRL: 1/512 + TPHA OD: PRI Intravenous penicillin: 14 days OD: Macular pucker (21 weeks) OD: 20/63
OS: HM CSF: + VDRL
Pleocytosis
HIV: negative
OS: PRI, NRC Prednisone: 60 mg/day (tapering regimen for 7 weeks) OS: Tractional RD (8 weeks) OS: CF
Case 2 OD: HM Serum: + VDRL: 1/1024 + TPHA OD: NRC Intravenous penicillin: 21 days OD: Mixed RD (2 weeks) OD: LP
OS: HM CSF: + VDRL
Pleocytosis
HIV: positive
OS: NRC Prednisone: 60 mg/day (tapering regimen for 7 weeks) OS: Mixed RD (1 week) OS: 20/150
Case 3 OD: CF Serum: + VDRL:1/4096 + THPA OD: NRC Intravenous penicillin: 21 days OD: Macular Pucker (5 weeks) OD: 20/250
OS: HM CSF: + VDRL
Pleocytosis
HIV: negative
OS: PPCR, PRI, NRC Prednisone: 60 mg/day (tapering regimen for 10 weeks) OS: Mixed RD (4 weeks) OS: HM
Case 4 OD: HM Serum: + VDRL: 1/512 + THPA OD: NRC Intravenous penicillin: 21 days OD: Tractional RD (2 weeks) OD: NLP
OS: 20/200 CSF: − VDRL
HIV: positive
OS: Optic disc hyperemia, vascular sheathing Prednisone: 60 mg/day (tapering regimen for 4 weeks) OS: No lesions OS: 20/20
  1. BCVA best corrected visual acuity, OD right eye, OS left eye, HM hand movements, VDRL Venereal Disease Research Laboratory, TPHA Treponema pallidum hemagglutination assay, CSF cerebrospinal fluid, HIV human immunodeficiency virus, PRI punctate inner retinal infiltrates, NRC necrotizing retinochoroiditis, RD retinal detachment CF, counting fingers, LP light perception PPCR, posterior placoid chorioretinitis, NPL no light perception
  2. aThe time indicated in brackets refers to interval between initial diagnosis and moment that the complication occurred / was detected.