Endogenous fungal endophthalmitis: risk factors, clinical features, and treatment outcomes in mold and yeast infections

Journal of Ophthalmic Inflammation and Infection

Table 2 Systemic risk factors for endogenous fungal endophthalmitis

Risk factor	Yeast (%)	Mold (%)	p value
Recent hospitalization	26/39 (66.7%)	9/14 (64.3%)	0.872
Recent surgery	12/39 (30.8%)	4/14 (28.6%)	0.878
Any immunocompromise	20/39 (51.3%)	9/14 (64.3%)	0.402
Iatrogenic	3/39 (7.7%)	8/14 (57.1%)	0.001
Diabetes mellitus	7/39 (17.9%)	4/14 (28.6%)	0.589
Cancer	9/39 (23.1%)	3/14 (21.4%)	0.899
HIV	3/39 (7.7%)	0/14 (0.0%)	0.285
Any IV/IVDU/catheter/HD	16/39 (41.0%)	10/14 (71.4%)	0.010
IVDU	6/39 (15.4%)	4/14 (28.6%)	0.279
Indwelling catheter	3/39 (7.7%)	0/14 (0.0%)	0.285
History of transplant	1/39 (2.6%)	5/14 (35.7%)	0.002
Positive systemic culture^a	10/39 (25.6%)	2/14 (14.3%)	0.384

HIV, human immunodeficiency virus; IV, intravenous line; IVDU, intravenous drug use; HD, hemodialysis port; Pearson chi-square test used for statistical analysis. ^a Positive systemic cultures for yeast included blood (7), urine (2), and cerebrospinal fluid (1). Positive systemic cultures for mold included sputum (2).