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Table 12 Flare value measured by LFCM by treatment and visit (ITT)

From: Phase II placebo-controlled study of nepafenac ophthalmic suspension 0.1% for postoperative inflammation and ocular pain associated with cataract surgery in Japanese patients

  

Day 1

Day 3

Day 7

Day 14

Nepafenac group

Mean

20.6

20.6

13.4

11.4

Std

24.6

40.9

12.2

9.1

N

101

103

103

103

Min

0.5

0.3

0.4

0.3

Max

153.2

396.7

57.8

57.8

Placebo group

Mean

24.3

47.5

65.6

52.0

Std

34.4

49.8

77.7

69.9

N

101

104

104

104

Min

1.8

2.5

2.5

1.5

Max

307.6

333.9

479.7

479.7

P value

 

0.6201

<0.0001

<0.0001

<0.0001

  1. Non-baseline P values are LSMeans by visit; test = repeated measure ANOVA, main effect of treatment P < 0.0001; treatment by visit interaction P < 0.0001
  2. Min minimum, Max maximum, Std standard deviation