Subretinal pigment epithelial infiltrates in primary vitreoretinal lymphoma

Daniel Vítor Vasconcelos-Santos; Gustavo Henrique De Puy e Souza; Bernardo Bacelar de Faria; Moisés Salgado Pedrosa; André Vasconcellos Diniz; Juliana Lambert Oréfice; Rogério Alves Costa; Fernando Oréfice

doi:10.1007/s12348-011-0034-x

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Subretinal pigment epithelial infiltrates in primary vitreoretinal lymphoma

Daniel Vítor Vasconcelos-Santos^{1, 2, 3}Email author,
Gustavo Henrique De Puy e Souza¹,
Bernardo Bacelar de Faria¹,
Moisés Salgado Pedrosa¹,
André Vasconcellos Diniz²,
Juliana Lambert Oréfice²,
Rogério Alves Costa² and
Fernando Oréfice²

Journal of Ophthalmic Inflammation and Infection20111:34

https://doi.org/10.1007/s12348-011-0034-x

Received: 10 June 2011
Accepted: 18 July 2011
Published: 6 August 2011

Keywords

Public Health
Lymphoma
Optical Coherence Tomography
Lymphoma Cell
Pigment Epithelium

A 67-year-old woman with chronic bilateral intraocular inflammation associated with vitreous cells and subretinal pigment epithelium (RPE) infiltrates (A–B) underwent a chorioretinal biopsy in the left eye after three negative vitreous biopsies. Sub-RPE deposits on spectral domain optical coherence tomography (C) corresponded to collections of diffuse large B-cell lymphoma cells on histopathogy (D–E) and immunohistochemistry (F–H).

Declarations

Acknowledgment

The authors acknowledge Victório Vinciguerra Neto, COMT for his work in capturing part of the images.

Conflict of interest

The authors have no financial interest to disclose.

Authors’ Affiliations

(1)

Department of Pathology, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil

(2)

Centro Brasileiro de Ciências Visuais, Belo Horizonte, Brazil

(3)

Rua dos Ottoni 881/1001, Belo Horizonte, MG, 30150-270, Brazil

Copyright

This article is published under license to BioMed Central Ltd. Open Access This article is distributed under the terms of the Creative Commons Attribution License which permits any use, distribution and reproduction in any medium, provided the original author(s) and source are credited.