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Table 1 Studies on surgical interventions in pediatric uveitic glaucoma – success rates

From: Uveitic glaucoma in children: a systematic review on surgical outcomes

 

Criteria for success (C = complete / Q = qualified)

Success rate

Author, Year

Type of surgery

Previous interventions

No. of Eyes

No. of Patients

Age at Surgery (yrs)

IOP (mmHg)

Meda

No. of proceduresb

Other

1 yr

2 yrs

 ≥ 5 yrs

Kanski and McAllister,’85 [23]

Trabeculo- dialysis

43% CPCb,37% filtration surgery

30

23

16 (4–36)c

 < 22

C: 0

Q: no limitation

1

  

C: 17%

Q: 60%

 

Freedman et al.,’02 [9]

Goniotomy

no

16

12

15 (6.5–30)c

 < 22, > 5

no limitation

1–2

no adverse events

1x: 72%d

2x: 79%

1x: 54%d

2x: 75%

1x:54%d

2x:75%

Ho et al.,’04 [20, 21]

Goniotomy

few cases had a TE before

40

31

10.3 ± 4.7e

 < 22, > 5

no limitation

1–3

 

 > 1x:92%

1x: 61%d

 > 1x: 92%

1: 47%d

 > 1x:81%

Bohnsack and Freedman,’13 [24]

Goniotomy

no

31

31

10.9 ± 4.4e

 < 22, > 5

no limitation

1–2

no adverse events

1x: 76%d

2x: 83%

1x: 57%d

2x: 79%

1x: 48%d

2x: 69%

Wang et al.,’16 [25]

Trabeculo-tomy

18% goniotomy

7% Ahmed implant

28

22

9.7 ± 3.6e

 < 22, > 5

no limitation

1–2

 

1x: 81%d

2x: 86%

1x: 69%d

2x: 77%

 

Heinz et al.,’11 [26]

TEf

88% CPCb

16

16

12.7 ± 3.8

 < 22, > 5

C: 0

Q: no limitation

1

  

C: 88%

Q: 94%

 

Wiese et al., ‘14 + ’16 [19, 27]

TEf

61% CPCb

21

17

13.8 ± 4e

 < 15, > 5

C: 0

Q: no limitation

1

 

C: 55%

Q: 70%

 

C: 38%

Q: 71%

Leinonen et al.,’15 [28]

TEf

24% CPCb, 7% viscocanalostomy

15d

14f

15d

14f

11.8 (6.3–20.4)g,c

11.0 (3.1–16.8)c,h

 < 22, > 5

0

1

 

73%g

57%h

 

73%g

16%h

Gautam et al.,’18 [6]

TEf

no

13

9

 ≤ 16

 < 22, > 5

C: 0

Q: no limitation

1

  

C: 54%^i

Q: 23%

 

Valimaki et al., ‘97 [29]

Molteno shunt

52% TEh, 22% CPCb

27

19

15.3 ± 8.7 e

 < 22, > 5

No more as used pre-opj

1

no loss of light perception

 

95%

89%

Chen et al.,’15 [22]

Ahmed implant

 

24

 

9.0 ± 3.8 e

 < 22, > 5 + 20% IOP reduction

no limitation

1 + revision of GDI accepted

no adverse events

  

75%

Wiese et al.,’16 [19]

Ahmed implant

54% TEh, 45% CPCb, 27% goniotomy

11

11

17.8 ± 6.1e

 < 15, > 5

0

1

    

Eksioglu et al., ‘17 [30]

Ahmed implant

25% TEh

16

11

14.2 ± 3.3e

 < 22, > 5

C: 0

Q: no limitation

1 + small revisions accepted

 

C: 56%

 

C: 38%

Q: 44%

Heinz et al., ‘06 [31]

CPC procedure

no

19

12

10.9 ± 3.4e

 < 22

C: 0

Q: no limitation

1–3

 

C: 0%

Q: 32%

  
  1. aNumber of IOP lowering medications that is accepted
  2. bCyclophotocoagulation
  3. cBased on mean (range) 
  4. dAfter 1 or 2 procedures, based on Kaplan–Meier survival analysis
  5. eBased on mean ± SD
  6. fTrabeculectomy
  7. gGroup using Tumor Necrosis Factor Inhibitors
  8. hControl group without the use of TNFI
  9. iAfter a mean follow-up of 2.3 ± 1.6 years
  10. jBefore operation