Fig. 8From: Vogt-Koyanagi-Harada disease: the step-by-step approach to a better understanding of clinicopathology, immunopathology, diagnosis, and management: a brief reviewFour main signs detected with ICGA in acute initial-onset VKH disease. A Hyperfluorescent disc (usually hypofluorescent on ICGA), which indicates severe inflammation. B Early hyperfluorescent vessels. C Numerous, regularly distributed hypofluorescent dark dots (HDDs), evenly sized, over the whole fundus, is the most demonstrative and quantifiable ICGA sign. D (top) Fuzzy, indistinct choroidal vessels represent the fourth ICGA sign; (Bottom) After 3 days of intravenous methylprednisolone treatment, the course and structure of choroidal vessels are again distinctly visibleBack to article page