Skip to main content
Fig. 6 | Journal of Ophthalmic Inflammation and Infection

Fig. 6

From: Choroidal involvement in systemic vasculitis: a systematic review

Fig. 6

Color fundus photography, dual fluorescein-indocyanine green angiography and optical coherence tomography imaging of a 63 year-old woman who presented with photopsias and loss of vision after tapering oral corticosteroid given in combination with azathioprine for the treatment of granulomatosis with polyangiitis diagnosed 2 months prior. Montage color fundus photographs of the right (top row, first frame) and the left (middle row first frame) eye show myelinated nerve fibers obscuring the optic disc margins, deep creamy-white serpiginoid choroiditis involving the posterior pole in both eyes and inferonasal to the disc in the left eye. Fundus autofluorescence imaging shows a granular pattern of hyper- and hypoautofluorescence of the lesions in the right (top row, second frame) and the left eye (middle row, second frame). Dual fluorescein-indocyanine green angiography frames at 8 min show window defects and staining on fluorescein angiography and diffuse hypofluorescence of the lesions on indocyanine green angiography in the right (top row, third and fourth frames, respectively) and the left eye (middle row, third and fourth frames, respectively). EDI-OCT of the left eye shows loss of outer retinal layers, RPE irregularities, thickening of the choroid, and hyperreflective dots in the choroid in the involved area (bottom row, left). After intravenous pulse methylprednisolone 1 g for 3 days, EDI-OCT shows partial improvement of RPE irregularity and reduced thickening of the choroid (bottom row, right). Visual acuity increased from counting fingers in both eyes to 20/40 in the right and 20/32 in the left eye. Active and latent tuberculosis had already been ruled out and the patient subsequently received cyclophosphamide therapy

Back to article page