From: Ocular inflammatory events following COVID-19 vaccination: a multinational case series
Variable | Total (%) (N = 70) | Anterior Uveitis (%) (N = 41) | Posterior Uveitis (%) (N = 9) | Scleritis (%) (N = 7) | Others (%) (N = 13) | |
---|---|---|---|---|---|---|
Previous Ocular Inflammatory Events | Number of patients | 36 (51.4) | 23 (56.1) | 3 (33.3) | 5 (71.4) | 5 (38.5) |
Controlled more than 3 months | 28 (82.4) | 17 (81.0) | 3 (100) | 3 (60.0) | 5 (100) | |
On Topical Anti-inflammatory | 1 (2.8) | 1 (4.3) | 0 (0.0) | 0 (0.0) | 0 (0.0) | |
On Systemic Anti-inflammatory | 7 (19.4) | 4 (17.4) | 0 (0.0) | 1 (20.0) | 2 (15.4) | |
Event similar to previous events | 34 (94.4) | 23 (100.0) | 2 (66.7) | 5 (100.0) | 4 (80) | |
Presentation | Unilateral | 60 (85.7) | 33 (80.5) | 8 (88.9) | 7 (100) | 12 (92.3) |
Bilateral | 10 (14.3) | 8 (19.5) | 1 (11.1) | 0 (0.0) | 1 (7.7) | |
VA Unaffected | 38 (54.3) | 22 (53.7) | 2 (22.2) | 6 (85.7) | 8 (61.5) | |
VA reduced ≤ 3 lines | 18 (25.7) | 10 (24.4) | 4 (44.4) | 1 (14.3) | 3 (23.1) | |
VA reduced > 3 lines | 14 (20.0) | 9 (22.0) | 3 (33.3) | 0 (0.0) | 2 (15.4) | |
Management | Topical Corticosteroids | 48 (68.6) | 34 (82.9) | 3 (33.3) | 6 (85.7) | 5 (38.5) |
Systemic Corticosteroids | 13 (18.6) | 2 (4.9) | 6 (66.7) | 1 (14.3) | 4 (30.8) | |
Antivirals | 6 (8.6) | 5 (12.2) | 0 (0.0) | 0 (0.0) | 1 (7.7) | |
NSAIDs | 2 (2.9) | 0 (0.0) | 0 (0.0) | 1 (14.3) | 1 (7.7) | |
Antibiotics | 4 (5.7) | 0 (0.0) | 4 (44.4) | 0 (0.0) | 0 (0.0) | |
Visual Outcomes | VA Unaffected | 65 (92.9) | 39 (95.1) | 7 (77.8) | 7 (100) | 12 (92.3) |
VA reduced ≤ 3 lines | 2 (2.9) | 1 (2.4) | 0 (0.0) | 0 (0.0) | 1 (7.7) | |
VA reduced > 3 lines | 3 (4.3) | 1 (2.4) | 2 (22.2) | 0 (0.0) | 0 (0.0) | |
Complications | Transient IOP elevation | 3 (4.3) | 3 (7.3) | 0 (0.0) | 0 (0.0) | 0 (0.0) |
Nummular Corneal Lesions | 1 (1.4) | 1 (2.4) | 0 (0.0) | 0 (0.0) | 0 (0.0) | |
Cystoid Macular Oedema | 2 (2.9) | 1 (2.4) | 0 (0.0) | 0 (0.0) | 1 (7.7) | |
Macular Scarring | 2 (2.9) | 0 (0.0) | 2 (22.2) | 0 (0.0) | 0 (0.0) |