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Table 1 Imaging features of acute posterior multifocal placoid pigment epitheliopathy (APMPPE)

From: Acute posterior multifocal placoid pigment epitheliopathy (APMPPE)

 

FFA

ICGA

FAF

SD-OCT

EDI-OCT

OCT-A

APMPPE

Active disease

Early hypofluorescence, late hyperfluorescence

Early and late hypofluorescence

Initial hypoautofluorescence, with progressive increase in hyperautofluorescence

Disruption of the outer retinal and ellipsoid zone, with hyperreflective material at the level of the outer retinal layers and RPE

Choroidal thickening

Areas of flow void at the level of the choriocapillaris

Healed disease

Early and late hyper and hypofluorescence reflecting RPE disturbance (window defect and pigmentary changes)

Normalisation

Mixed pattern of hypoautofluorescence and hyperautofluorescence, followed by homogenous hypoautofluorescent

Either partial restoration of outer retina or focal areas of photoreceptors/RPE atrophy

Normalisation of choroidal thickness

Normalisation of choriocapillaris flow

  1. FFA: fundus fluorescein angiography; ICGA: indocyanine angiography; FAF: fundus autofluorescence; SD-OCT: spectral domain optical coherence tomography; EDI-OCT: enhanced deep imaging optical coherence tomography; OCT-A: optical coherence tomography angiography; RPE: retinal pigment epithelium