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Fig. 3 | Journal of Ophthalmic Inflammation and Infection

Fig. 3

From: Histopathological, immunohistochemical and molecular biologic study of an enucleated specimen of a case of Eales’ disease

Fig. 3

Scanner view of eyeball showing a thick epiretinal membrane which is densely fibrotic, scarred, relatively avascular and flanked above and below by metaplastic bone (arrow). Inflammation is seen below the membrane (asterix) [A]. Higher magnification of inflammatory focus shows collections of epithelioid cells forming an ill formed granuloma [B]. The epithelioid histiocytes are CD68+ [C] and lymphoid cells are predominantly CD3+ [D], CD8+ cytotoxic in phenotype [E] without CD4+ T cells [F] and CD20+ B cells [G]. (Magnification A: H&E obj.× 4, B: H&E obj.× 20, C: CD68 obj.× 20, D: CD3 obj.× 20, E: CD8 obj.× 20, F: CD4 obj.× 20, F: CD20 obj.× 20)

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