Table 1 Clinical presentations of CMV retinitis in patients of NHL
From: Cytomegalovirus retinitis in patients of non-Hodgkin’s lymphoma: clinical presentations and outcomes
Month and year of presentation | AC reaction/ Vitritis | Duration of onset of CMV after initial diagnosis of NHL | Type of CMV retinitis | CD 4 count at presentation (cells/ mm3) | Adverse effects of Valganciclovir | Time for reactivation after stopping maintenance Phase/ CD4 count at the time of recurrence | PCR | Total duration of follow up | |
|---|---|---|---|---|---|---|---|---|---|
Case 1 | September 2018 | AC Cells 1+,Vitritis 1+ | 12 months | Granular to start and later turned to fulminant | 109 | Nil | First recurrence 16 days CD4 counts - 130 cells/ mm3 Second Recurrence 32 days CD4 counts 219 cells/mm3 | CMV | 22 months |
Case 2 | October 2019 | RE Vitritis 3+ | 11 months | Granular | 278 | Nil | on maintenance regimen | CMV | 4 months |
Case 3 | June 2015 | AC cells 2+,Vitiritis 1+ | 18 months | Granular | 180 | N/A | No recurrence | Negative | 4 months |
Case 4 | January 2019 | AC Cells 1+, Vitritis 1+ | 20 months | Mixed | 186 | Neutropenia | First recurrence 35 days CD4 counts - 370 cells/ mm3 Second Recurrence 42 days after stopping maintenance regimen CD4 counts: 350 cells/ mm3 Third Recurrence 44 days after stopping maintenance regimen CD4 counts: 970 cells/ mm3 | CMV | 15 months |