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Table 1 Antimicrobial activities of delafloxacin, levofloxacin, and moxifloxacin tested against intravitreal Staphylococcus isolates

From: In vitro Susceptibilities of Methicillin-Susceptible and Resistant Staphylococci to Traditional Antibiotics Compared to a Novel Fluoroquinolone

Organism

Rates of resistance

All isolates

MIC90a

MSSAb

MIC90

MSSEc

MIC90

MRSAd

MIC90

MRSEe

MIC90

Levofloxacin

60% (26/43)

8.0

50% (2/4)

--

60% (6/10)

8.0

83% (5/6)

--

54% (13/24)

8.0

Moxifloxacin

50% (22/44)

8.0

50% (2/4)

--

55% (6/11)

8.0

83% (5/6)

--

54% (13/24)

8.0

Delafloxacin

12% (12/43)

1.0

0% (0/4)

--

27% (3/11)

0.8

33% (2/6)

--

25% (6/24)

0.8

  1. aMIC90, minimum inhibitory concentration at which growth of 90% of organisms is inhibited, expressed in micrograms per milliliter (μg/ml), which were only calculated for microbes with more than 10 isolates
  2. bMSSA, methicillin-sensitive S. aureus
  3. cMRSA,methicillin-resistant S. aureus
  4. dMSSE, methicillin-sensitive S. epidermidis
  5. eMRSE, methicillin-resistant S. epidermidis