Intravenous administration of Penicillin results in therapeutic intravitreal levels in chronic postoperative endophthalmitis

Journal of Ophthalmic Inflammation and Infection

Table 1 Intravitreal Penicillin and Ampicillin Concentrations

Drug	Route	Dosing regimen	Intravitreal concentration	Range of quantitation
Penicillin	Intravenous	4 million U q4h	3.5μg/ml^a	0.06-5μg/ml
Ampicillin	Intravitreal	5 mg (5000μg/0.1 ml) last administered 48 h prior	0.3μg/ml^a	0.12–2.5μg/ml