Fig. 3

Multimodal imaging analysis of the macular and peripapillary area of the right eye showing multiple lesions at different stages of acute posterior multifocal placoid pigment epitheliopathy (APMPPE). Images a, b, c and d were taken 3 days after onset of symptoms. a Color image of the fundus showing fresh lesions. b En face reconstruction of the choriocapillaris flow by optical coherence tomography angiography (OCTA) demonstrating an area of lacking signal. c Structural OCT with superimposed flow signal revealing areas with decreased flow signal. d Early phase indocyanine green angiography (IA) with a hypocyanescent area corresponding to clinically visible early lesions. Images e, f, g, and h were taken 6 months after the onset of symptoms. e Color image of the fundus showing old macular lesions. f, g En face reconstruction of the choriocapillaris flow by OCTA demonstrating an increased area of low signal compared to b and c, respectively. g Structural OCT with superimposed flow signal revealing an increase of low signal compared to c. h Early-phase IA showing almost no sign of the hypocyanescent area seen in d