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Journal of Ophthalmic Inflammation and Infection

Table 1 Comparison of characteristics between patients with persistent post-operative iritis versus control group with associated p values

From: Evaluation of the etiology of persistent iritis after cataract surgery

Characteristic

Control group

Iritis group

Sample size (n)

All control patients

All iritis patients

p value

Excluding prior inflammation/diagnosis

p value

Iritis > 6 months and no prior Inflammation/diagnosis

p value

Patients

40

39

–

22

–

9

–

Demographic

 Mean age (years) ± standard deviation

66.7 ± 10.4

65.8 ± 14.1

0.76

69.1 ± 12.5

0.417

70.8 ± 16.6

0.345

 Female sex [n (%)]

25 (63)

30 (77)

0.163

17 (77)

0.234

6 (67)

1.00

 African American race [n (%)]

11 (28)

34 (87)*

< 0.001

22 (100)*

< 0.001

9 (100)*

< 0.001

Clinical history [n (%)]

 Prior ocular inflammation

0

13 (33)

 

–

–

–

–

 Prior ocular trauma

0

2 (5)

0.241

1 (5)

0.355

1 (11)

0.184

Comorbidities [n (%)]

 Underlying systemic diagnosis†

0

9 (23)

 

–

–

–

–

 Glaucoma

13 (33)

11 (28)

0.678

5 (23)

0.417

3 (33)

1.00

 Diabetes

11 (28)

12 (31)‡

0.749

11 (50)

0.076

6 (67)*

0.049

Intra-operative finding [n (%)]

 Use of ring/hooks

1 (3)

9 (23)*

0.007

2 (9)

0.285

2 (22)

0.083

  1. *Significant at the 0.05 probability level
  2. †The diagnoses were as follows: ulcerative colitis (1), sarcoidosis (4), multiple sclerosis (2), rheumatoid arthritis (1), ankylosing spondylitis (1), and HSV (1)
  3. ‡Of the 12 patients in this group, 0 had a recent intravitreal injection, and the peri-operative HbA1c ranged from 5.9–7.8%. Four of these patients had documented DR without cystoid macular edema (CME). One patient with diabetes was noted to have CME not due to DR. Two other patients were found to have pre-existing CME without the diagnosis of diabetes
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