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Table 1 Comparison of characteristics between patients with persistent post-operative iritis versus control group with associated p values

From: Evaluation of the etiology of persistent iritis after cataract surgery

Characteristic Control group Iritis group
Sample size (n) All control patients All iritis patients p value Excluding prior inflammation/diagnosis p value Iritis > 6 months and no prior Inflammation/diagnosis p value
Patients 40 39 22 9
Demographic
 Mean age (years) ± standard deviation 66.7 ± 10.4 65.8 ± 14.1 0.76 69.1 ± 12.5 0.417 70.8 ± 16.6 0.345
 Female sex [n (%)] 25 (63) 30 (77) 0.163 17 (77) 0.234 6 (67) 1.00
 African American race [n (%)] 11 (28) 34 (87)* < 0.001 22 (100)* < 0.001 9 (100)* < 0.001
Clinical history [n (%)]
 Prior ocular inflammation 0 13 (33)  
 Prior ocular trauma 0 2 (5) 0.241 1 (5) 0.355 1 (11) 0.184
Comorbidities [n (%)]
 Underlying systemic diagnosis† 0 9 (23)  
 Glaucoma 13 (33) 11 (28) 0.678 5 (23) 0.417 3 (33) 1.00
 Diabetes 11 (28) 12 (31)‡ 0.749 11 (50) 0.076 6 (67)* 0.049
Intra-operative finding [n (%)]
 Use of ring/hooks 1 (3) 9 (23)* 0.007 2 (9) 0.285 2 (22) 0.083
  1. *Significant at the 0.05 probability level
  2. †The diagnoses were as follows: ulcerative colitis (1), sarcoidosis (4), multiple sclerosis (2), rheumatoid arthritis (1), ankylosing spondylitis (1), and HSV (1)
  3. ‡Of the 12 patients in this group, 0 had a recent intravitreal injection, and the peri-operative HbA1c ranged from 5.9–7.8%. Four of these patients had documented DR without cystoid macular edema (CME). One patient with diabetes was noted to have CME not due to DR. Two other patients were found to have pre-existing CME without the diagnosis of diabetes