The ghost of the great imitator: prognostic factors for poor outcome in syphilitic uveitis

Journal of Ophthalmic Inflammation and Infection

Table 2 Prognostic factors associated with syphilitic posterior uveitis in 44 patients

	Final BCVA < 1.0 (20/200)	Final BCVA > 1.0 (20/200)	p value
Sex
Male	11 (84.6)	20 (64.5)	0.282*
Female	2 (15.4)	11 (35.5)	0.282*
Age (mean per eye)	51.7 ± 18.3	40.5 ± 15.9	0.070**
HIV coinfection
Positive	5 (38.5)	7 (25.0)	0.469*
Negative	8 (61.5)	21 (75.0)	0.469*
Median VDRL titer	1/512 [0–4096]	1/64 [0–4096]	0.004**
Prior inadvertent use of systemic steroids
Yes	7 (53.8)	2 (6.4)	0.001*
No	6 (46.2)	29 (93.6)	0.001*
Presence of necrotizing retinochoroiditis
Yes	6 (46.2)	5 (16.1)	0.057*
No	7 (53.8)	26 (83.9)	0.057*
Mean time of symptoms before diagnosis (days)	176.8 ± 250.2	74.8 ± 133.1	0.024**
Mean initial BCVA (LogMAR)	2.1 ± 0.6	1.1 ± 0.7	< 0.001**

Continuous variables are expressed as median [range] or mean ± standard deviation
Categorical variables are expressed as absolute number (%)
BCVA Best-corrected visual acuity
*Fisher’s exact test
**Mann-Whitney U test