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Table 2 Prognostic factors associated with syphilitic posterior uveitis in 44 patients

From: The ghost of the great imitator: prognostic factors for poor outcome in syphilitic uveitis

  Final BCVA < 1.0 (20/200) Final BCVA > 1.0 (20/200) p value
Sex
 Male 11 (84.6) 20 (64.5) 0.282*
 Female 2 (15.4) 11 (35.5)
 Age (mean per eye) 51.7 ± 18.3 40.5 ± 15.9 0.070**
HIV coinfection
 Positive 5 (38.5) 7 (25.0) 0.469*
 Negative 8 (61.5) 21 (75.0)
Median VDRL titer 1/512 [0–4096] 1/64 [0–4096] 0.004**
Prior inadvertent use of systemic steroids
 Yes 7 (53.8) 2 (6.4) 0.001*
 No 6 (46.2) 29 (93.6)
Presence of necrotizing retinochoroiditis
 Yes 6 (46.2) 5 (16.1) 0.057*
 No 7 (53.8) 26 (83.9)
Mean time of symptoms before diagnosis (days) 176.8 ± 250.2 74.8 ± 133.1 0.024**
Mean initial BCVA (LogMAR) 2.1 ± 0.6 1.1 ± 0.7 < 0.001**
  1. Continuous variables are expressed as median [range] or mean ± standard deviation
  2. Categorical variables are expressed as absolute number (%)
  3. BCVA Best-corrected visual acuity
  4. *Fisher’s exact test
  5. **Mann-Whitney U test