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Table 2 Cytokines detected in tears of JIA-U and I-CAU in this study and from aqueous humor in previous studies

From: Discovery of tear biomarkers in children with chronic non-infectious anterior uveitis: a pilot study

Authors, year

Disease a (n)

Samples

Cytokines/chemokines

Direction

Present findings JIA-U vs. I-CAU

Haasnoot, 2016 [9]

JIA-U [21]

CAU [15]

IU [28]

Controls [8]

AqH

IL-29/ IFN-λ1

Decreased in JIA-U vs CAU, IU and controls

Not detected

  

LAP

Increased in JIA-U vs IU and controls

Decreased

  

S100A8

Decreased JIA-U vs. IU

Increased

  

sCD14

Increased JIA-U vs. controls

Increased

Walscheid, 2015 [12]

JIA-U [17]

IAU [12]

Controls [16]

AqH

S100A8

Increased JIA-U and IAU vs. controls

Increased

  

S100A9

Increased JIA-U and IAU vs. controls

Decreased

Ayuso, 2013 [8]

JIA-U [14]

CAU [8]

Other Uveitis [30]

Controls [20]

AqH

TTR

Increased JIA-U and CAU vs. other uveitis and controls

Increased

  1. JIA-U JIA-associated uveitis, CAU chronic anterior uveitis, IU idiopathic uveitis which included non-anterior uveitis, IAU idiopathic anterior uveitis, IL-29/IFN-λ1
  2. interleukin-29/interferon-λ1, LAP latency associated peptide, S100 S100 calcium binding protein, sCD14 soluble cluster of differentiation 14, TTR transthyretin
  3. aDisease categories are listed are as they were presented in each study and do not necessarily conform to our disease descriptions