Fig. 3

Multimodal imaging of inflammatory choroidal neovascularization (CNV) (medusa head appearance) in a case of multifocal choroiditis. a The optical coherence tomography line scan passing through the fovea shows a hyper-reflective lesion in the outer retina with the presence of mild subretinal fluid suggestive of a type 2 CNV. b, c Optical coherence tomography angiography (OCTA) en face 3 × 3 mm scan (along with structural en face OCT scan) confirms the presence of a CNV lesion with a medusa head appearance. Similar to Fig. 2, manual segmentation of the scan has been performed to obtain a slab of 60 μm thickness including the outer retina and choriocapillaris to allow better delineation of the CNV. d The OCT line scan at 8-month follow-up after one injection of intravitreal ranibizumab shows the persistence of outer retinal hyper-reflectivity but resolution of subretinal fluid. e, f At this visit, the OCTA en face scan (with corresponding structural en face scan) shows a decrease in the size of the CNV lesion along with a decrease in vessel caliber and branching