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Fig. 2 | Journal of Ophthalmic Inflammation and Infection

Fig. 2

From: An update on inflammatory choroidal neovascularization: epidemiology, multimodal imaging, and management

Fig. 2

Multimodal imaging in a case of peripapillary inflammatory choroidal neovascularization (CNV) (sea fan type). a Combined fluorescein angiography (FA) and indocyanine green angiography (ICGA) show multiple round hypofluorescent lesions in the mid-periphery with early ill-defined hyperfluorescence on FA and area of hypocyanescence with ill-defined choroidal vessels on ICGA temporal to the optic disc. b In the late phase FA, the mid-peripheral hypofluorescent lesions become less hypofluorescent/isofluorescent. There is a progressive increase in the hyperfluorescence temporal to the optic disc on FA, suggestive of type 2 choroidal neovascularization. c Optical coherence tomography angiography en face scan shows the presence of neovascular loops of vessels which have a sea fan configuration although the feeder vessel is not apparent (yellow dashed circle). The scan has been obtained by manually segmenting the image to obtain a slab of 60 μm thickness including the outer retina and choriocapillaris to allow better delineation of the pathology. d The corresponding structural en face scan does not show any signal loss except in the areas of hard exudates. e The optical coherence tomography line scan passing through the area of CNV shows the presence of a hyper-reflective lesion in the outer retina in the peripapillary region suggestive of type 2 CNV associated with retinal thickening and intraretinal cystoid spaces

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