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Table 1 Chronology of major events

From: Panuveitis-like reaction following encircling laser retinopexy/cerclage in a 21-year-old male

Week 1

Day 1 post-laser

 • Hand motion, light perception in all quadrants vision

 • + 3 brown cells, + 2 flare in anterior chamber; dense vitreous haze on dilated indirect ophthalmoscopy

 • IOP 20 mmHg treated eye, 10 mmHg RRD eye

 • Topical polymyxin + neomycin + dexamethasone shifted to prednisolone acetate 10 mg/mL q2 hours, atropine sulfate 1% 3×/day, and oral acetazolamide 125 mg 2×/day

Day 2

• B-scan: low amplitude, mobile echoes in the mid to posterior vitreous, and prominent choroid (Fig. 1)

Day 4

 • 1-mm blood-tinged hypopyon (Fig. 2)

 • IOP of 10 mmHg

 • Topical prednisolone acetate increased to one drop hourly, topical moxifloxacin 5 mg/mL 6 drops q3 hours started

 • Subconjunctival triamcinolone acetonide (10 mg)

Day 6

 • Patient admitted to hospital

Day 8

 • Oral prednisone 60 mg daily

Week 2

 • Cells and flare decreased to between + 1 and + 2,

 • Hypopyon resolved day 13 (Fig. 3)

Week 3

 • Pupillary synechiae, iris swelling 6–12-o’clock areas; dense, mobile, gray-brown retrolental sheets/membranes (Fig. 4)

 • B-scan: dense vitreous cells greatest towards posterior vitreous; mobile mid-amplitude echoes in nasal wall suspicious for exudative retinal detachment (Fig. 5)

 • Ultrasound biomicroscopy: ciliary body cyst-like lesion and swelling, echoes in the space between the iris and lens 4–10 o’clock (Fig. 6)

 • Oral immunosuppressive therapy, pars plana vitrectomy contemplated ➔ deferred due to stable condition, fear of pushing eye into phthisis

Week 4

 • B-scan: same features but decreased amplitude of echoes

 • 20/200 vision with and without pinhole on day 27

 • 20/70 correcting to 20/20 on pinhole vision on day 36 (Fig. 7)

 • Fundus details first seen on indirect ophthalmoscopy day 30

Week 6

 • Oral prednisone gradually adjusted to 40–50 mg/day

Week 8

 • 20/20 uncorrected vision on day 59 with persistence of + 1 to 2 anterior chamber cells and flare, retrolental membrane (Fig. 11)

 • Macular OCT: generalized macular thickening > 99th percentile, preserved foveal anatomy, very visible posterior hyaloid face detached above the foveal depression (Fig. 8)

 • Fluorescein angiography: normal dye transit, focal non-specific parafoveal staining, no evidence of vasculitis, phlebitis, delayed filling, gross macular edema nor ischemia (Figs. 9 and 10)

 • B-scan: near-total resolution of previously observed lesions

Week 11

 • IOP ~ 25 treated eye, 30–35 RRD eye

 • Laser iridotomy and/or phacoemulsification contemplated ➔ deferred until resolution of inflammation

 • Timolol maleate 5 mg/mL 2×/day started

 • IOP decreased over following 2 days: 5–9 RRD eye, 17–19 treated eye (Figs. 11 and 12)