Fig. 2

Fundus photograph of the right eye after the initial healing response with interval improvement in the vitritis and disc edema. Multiple grayish lesions can be seen in the retinal periphery which appear healed (a). There was subsequent increase in number and size of these grayish-yellow choroidal lesions along with worsening of vitritis and recurrence of disc edema after 8 weeks of immunosupression (b). Fluorescein angiogram (FA) (in the early frame) showed optic disc hyperfluorescence and multiple areas of transmission hyperfluorescence scattered throughout the retinal periphery which were suggestive of healed lesions along with multiple hypofluorescent lesions suggestive of active choroidal lesions (c). Late frames of FA revealed disc hyperfluorescence along with hyperfluorescent lesions suggestive of active disease along with vessel wall hyperfluorescence suggestive of active vasculitis (d). Fundus autofluorescence image (with the ultra-wide field fundus camera) shows the presence of hypo-autofluorescent lesions with hyper-autofluorescent borders in the retinal periphery (e) as well as in the peripapillary region. These hypo-autofluorescent lesions with hyper-autofluorescent borders are also appreciated on conventional color fundus camera (f). The presence of such hypo-autofluorescent lesions did not favor the diagnosis of sympathetic ophthalmia raising the clinical suspicion of an alternate diagnosis