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Table 1 Reports of dematiaceous fungi in endogenous endophthalmitisa

From: Dematiaceous fungal endophthalmitis: report of a case and review of the literature

Reference # cases Dematiaceous fungi Related factors Treatment Outcome
Rao [5] 1 Alternaria alternata Contaminated intravenous fluids/catheter Intravitreal: vancomycin, amikacin, amphotericin
Intravenous: amphotericin, fluconazole
Topical and oral: fluconazole
VA hand movements
Weinberger [6] 1 Phialemonium curvatum Intracavernous injections; diabetes mellitus Intravitreal amphotericin B Enucleation
Zayit-Soudry [7] 1 Phialemonium curvatum Intracavernous injections; prosthetic aortic valve; endocarditis Intravitreal and intravenous: amphotericin B VA 20/2500
Silva-Vergara [8] 1 Sporothrix brasiliensis HIV infection Intravenous: amphotericin B Oral: itraconazole “Bilateral blindness”
Pavan [9] 1 Bipolaris hawaiiensis HIV infection Intravitreal and intravenous: amphotericin B
Oral: fluconazole
Resolved
Wu [10] 1 Cladosporium sp. Postpartum Intravitreal: fluconazole, amphotericin B, voriconazole Resolved
Lingappan [11] 1 Cladophialophora devriesii NA NA NA
Marangon [12] 2 Pleurostomophora sp. NA NA NA
Current report 1 Pleurostomophora richardsiae Mitral valve replacement; systemic steroids; Intravenous drug use Intravitreal: amphotericin B, cefazolin, and vancomycin
Intravenous: amphotericin B and voriconazole
Topical: ciprofloxacin and natamycin
VA light perception
  1. Cases include endogenous endophthalmitis due to dematiaceous fungi, not including cases in which the Scedosporium sp., or the related telomorph Pseudallescheria boydii, or Sporothrix schenckii were implicated
  2. NA not available, HIV human immunodeficiency virus, VA visual acuity