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Table 2 Comparisons of clinical and immunologic characteristics in subjects with or without CMV in aqueous humor

From: Cytomegalovirus as a cause of hypertensive anterior uveitis in immunocompetent patients

Characteristics

CMV-positive subjects n = 6

CMV-negative subjects n = 15

P value

Demographic characteristics

 Male, n (%)

6 (100 %)

13 (86.7 %)

0.500

 Age, years

47.5 ± 14.8

67.6 ± 11.8

0.006

Ocular characteristics

 Initial BCVA

0.65 ± 0.29

0.58 ± 0.29

0.569

 Final BCVA

0.47 ± 0.46

0.52 ± 0.30

0.733

 Spherical equivalent, D

-3.6 ± 4.2

0.0 ± 1.6

0.031

 Axial length, mm

25.7 ± 1.5

24.4 ± 0.7

0.053

 Glaucoma, n (%)

6 (100 %)

13 (86.7 %)

0.347

 Average RNFL thickness, μm

66.2 ± 16.7

77.8 ± 19.1

0.132

 Corneal endothelial cell count, mm2

1245 ± 560

1981 ± 387

0.009

 Unilaterality, n (%)

83.3

80.0

0.684

 KPs at baseline examination, n (%)

83.3

73.3

0.550

 Presence of PAS, n (%)

4 (66.7 %)

5 (33.3 %)

0.331

 Anterior chamber reaction with 1+ or less, n (%)

100.0

92.9

0.714

 Lens status, phakic, n (%)

5 (83.3 %)

5 (33.3 %)

0.055

 Baseline IOP, mmHg

28.83 ± 8.25

22.73 ± 7.86

0.132

 Maximum IOP, mmHg

37.17 ± 8.03

39.53 ± 13.02

0.622

 Final IOP, mmHg

13.3 ± 3.44

13.5 ± 5.05

0.950

Number of anti-glaucoma medication, n

2.67 ± 0.81

2.67 ± 0.81

0.970

Course of uveitis

  

0.544

 Chronic, n (%)

4 (66.7 %)

13 (86.7 %)

 

 Recurrent, n (%)

2 (33.3 %)

2 (13.3 %)

 

Glaucoma operation, n (%)

4 (66.7 %)

10 (66.7 %)

0.701

Choice of glaucoma operation

  

0.095

 Ahmed valve, n (%)

3 (75.0 %)

2 (20.0 %)

 

 Trabeculectomy or ExPRESS, n (%)

1 (25.0 %)

8 (80.0 %)

 

HSV PCR positivity, n (%)

0 (0.0 %)

1 (6.2 %)

0.727

CMV RQ PCR, copies/mL

46,048.8 ± 91,334.5

Negative

n/a

  1. CMV cytomegalovirus, BCVA best-corrected visual acuity, RNFL retinal nerve fiber layer, KP keratic precipitate, PAS peripheral anterior synechiae, n/a not applicable