Author (year) | Myasthenia gravis | Pure red cell aplasia | Other conditions encountered | Lymphopeniaa | Low CD3+ T cells (<672 cells/mL or <54 %) | Low CD4+ count (<360/μL or <36 %) | A low CD8+ count (<240 cells/μL) | Low CD4+/CD8+ ratio (<0.6) | Low NK cells (<130 cells/mL or <7.1 %) | Hypogammaglobulinemia IgG (IgG < 8 g/L) | Hypogammaglobulinemia IgM (IgM <0.5 g/L) | Hypogammaglobulinemia IgA (IgA < 1.1 g/L) | Panhypogammaglobulinemia (I gG < 8 g/L, IgM <0.5 g/L, IgA < 1.1 g/L, or total Ig < 9.6 g/L) | |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Previously published cases | Ho et al. (2010) [10] | − | − | None | + | + | + | − | + | + | + | + | + | + |
Mateo-Montoya et al. (2010) [11] | + | − | None | NR | NR | + | NR | NR | NR | NR | NR | NR | + | |
Park et al. (2009) [12] | − | − | None | + | NR | NR | NR | NR | NR | + | + | + | + | |
Sen et al. (2005) [13] | − | − | ?neurosensory hearing loss and optic neuropathy | NR | NR | + | NR | + | NR | + | + | + | + | |
Wan et al. (2012) [14] | NR | + | Autoimmune retinopathy (many years after diagnosis of retinitis) | NR | NR | NR | NR | NR | NR | NR | NR | NR | NR | |
Yong et al. (2008) [15] | − | − | None | + | − | + | − | + | NR | + | + | + | + | |
Assi et al. (2002) [16] case 1 | + | − | None | − | NR | + | NR | + | NR | − | − | + | − | |
Assi et al. (2002) [16] case 2 | − | − | None | NR | NR | NR | − | + | NR | + | + | + | + | |
Current case | Downes, et al. (2013) | − | + | None | − | − | − | − | − | − | + | + | + | + |
Summary | Total n = 9 | +2/8 reported (25.0 %) | +2/9 cases (22.2 %) | No other definite autoimmune conditions encountered at the time of diagnosis of retinitis | +3/5 reported (60.0 %) | +1/3 reported (33.3 %) | +5/6 reported (83.3 %) | +0/4 reported (0.0 %) | +5/6 reported (83.3 %) | +1/2 reported (50.0 %) | +7/8 reported hypo IgG (87.5 %) | +7/8 reported hypo IgM (87.5 %) | +8/8 reported hypo IgA (87.5 %) | +7/8 reported panhypogammaglobulins (87.5 %) |