Traumatic endophthalmitis caused by Nocardia kruczakiae in a patient with traumatic eye injury

Journal of Ophthalmic Inflammation and Infection

Table 1 Antimicrobial susceptibility of N. kruczakiae CNM997/10, the causal agent of endophthalmitis in the present patient

Antimicrobial agent	MIC (μg/ml)^a	Susceptibility^b	Resistance breakpoint^c
Primary^c
Amikacin	0.19	S	≥16
Amoxicillin/clavulanic acid	≥256	R	≥32/16
Ciprofloxacin	≥32	R	≥4
Clarithromycin	0.5	S	≥8
Imipenem	0.5	S	≥16
Linezolid	1	S	≤8
Trimethoprim/sulphamethoxazole	2/38	S	≥4/76
Tobramycin	≥256	R	≥16
Others^c,d
Ampicillin	≥256	R	≥32
Cefotaxime	≥32	R	≥64
Meropenen	8	–	Na
Gentamicin	8	I	≥16
Tetracycline	≥256	–	Na
Chloramphenicol	≥256	–	Na
Clindamycin	0.03	S	≥4
Quinupristin/dalfopristin	≥32	–	Na
Vancomycin	≥32	–	Na
Teicoplanin	≥256	–	Na

^aMinimum inhibitory concentration; ^bS and R, susceptible and resistant; ^cResistance and susceptibility breakpoints are those recommended by the CLSI 2011 M24-A2, and ^dby the NCCLS 2003 M24-A; Na, not available