Fig. 1From: IgG4-associated orbital and ocular inflammation a B-scan ultrasonography shows serous elevation of the retina in the right eye of case 1. b–d Histology of episcleral/orbital biopsy from case 1. b Chronic inflammation in a background of fibrosis is seen. In this field, there is a vasculo-centric component to the inflammation (arrows), along with a hyalinized vessel (arrowhead) (H&E stain, original magnification, ×200). c Higher magnification of another region exhibits mixed chronic inflammatory cells, including lymphocytes, plasma cells, and macrophages (H&E stain, original magnification, ×600). d IgG4 immunostain was positive in up to 50 plasma cells per high-power field, comprising over 50 % of the total plasma cell population (original magnification, ×400)Back to article page