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Table 1 Choroidal vasculature changes and choroidal thickness and volume values in convalescent VKH patients compared to controls

From: Choroidal atrophy and loss of choriocapillaris in convalescent stage of Vogt-Koyanagi-Harada disease: in vivo documentation

 

Patients

Controls

P value

No. 13 (22 eyes)

No. 9 (17 eyes)

Choroidal thickness, mean ± SD (range), μm

   

 Fovea

200 ± 60 (54 to 305)

288 ± 40 (229 to 350)

<0.0001 (Student's t test)

 Parafovea

209 ± 61 (46 to 3.5)

278 ± 36 (209 to 333)

<0.0001 (Student's t test)

 Entire macula

198 ± 58 (44 to 282)

268 ± 32 (202 to 318)

<0.0001 (Student's t test)

Choroidal volume, mean ± SD (range), μm

   

 Fovea

0.99 ± 0.31 (0.21 to 1.49)

1.49 ± 0.21 (1.17 to 1.82)

<0.000 (Student's t test)

 Parafovea

1.28 ± 0.37 (0.29 to 1.9)

1.75 ± 0.23 (1.32 to 2.11)

<0.0001 (Student's t test)

 Entire macula

5.33 ± 1.60 (1.01 to 7.33)

7.51 ± 0.93 (5.6 to 9.02)

<0.0001 (Student's t test)

Preservation of choroidal vessel layers

   

 Choriocapillaris-equivalent layer

11/22 (50%)

17/17 (100%)

<0.000 (chi-square)

 Medium choroidal vessels

22/22 (100%)

17/17 (100%)

1

 Large choroidal vessels

17/22 (77%)

17/17 (100%)

<0.000 (chi-square)

  1. Choroidal thickness and volume values in the eyes with convalescent Vogt-Koyanagi-Harada disease were significantly lower than those in controls. Also, the choriocapillaris and large choroidal vessels were significantly lost in convalescent Vogt-Koyanagi-Harada disease.