Comparative evolution of PIC lesions OS. (a) Fundus and red-free photograph, spectral domain optical coherence tomography (SD-OCT), and autofluorescence at baseline of our report (early 2010). (b) Active disease with multiple new lesions in the left eye 3 months later when the vision have fallento CF. Note the new lesions (regions indicated by arrows) on color photograph and autofluorescent image, and retinal pigment epithelium (RPE)/photoreceptor alterations (arrow) on SD-OCT image during active disease. No optic nerve edema or hyperemia is noted. (c) Most recent images following treatment demonstrating regression of some of the smaller lesions and enlargement of others. SD-OCT image showing RPE/photoreceptor loss in the areas of previously active lesions (arrow).