Fig. 1

Patient 1. a Fundus photograph of the right eye shows retinal hemorrhages, cotton-wool spots, and retinal pigment epithelial changes in the macular area. b Fundus photograph of the left eye shows retinal pigment epithelial changes. Mid-phase fluorescein angiogram of the left eye shows retinal pigment epithelium changes, retinal vascular leakage (c), and disseminated peripheral punctiform hyperfluorescence (d). e Mid-phase indocyanine green angiogram of the left eye showing areas of macular hypofluorescence (white arrow heads). f Late-phase indocyanine green angiogram of the same eye shows hyperfluorescent fleecy lesions in the midperiphery