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Table 3 Diagnosis, systemic involvement and risk factors for tuberculosis (n = 49 persons)

From: Clinical spectrum of tuberculous optic neuropathy

Variable

Number of patients (%)

Criteria used for diagnosis of tuberculosis

 

 •Consistent ocular signs

49 (100 %)

 •Positive response to antituberculous treatment

44 (89.8 %)

 •Positive Mantoux reaction

38 (77.6 %)

 •Positive IFN-gamma release assay

10 (20.4 %)

 •Active or old lesion(s) consistent with pulmonary tuberculosis on chest imaging

4 (8.2 %)

 •Identification of acid-fast bacilli by microscopy or culture

 

  •Extraocular

3 (6.1 %)

  •Intraocular

0 (0 %)

 •Positive M. tuberculosis PCR from ocular fluid

0 (0 %)

Systemic involvements

 

 •Pulmonary

8 (16.3 %)

 •Central nervous system: meningeal

4 (8.2 %)

 •Lymphatic

4 (8.2 %)

 •Othera

2 (4.1 %)

 •None

31 (63.3 %)

Risk factors

 

 •Lived in or travel to an endemic area

34 (69.4 %)

 •Personal or family history of tuberculosis

9 (18.4 %)

 •Diabetes mellitus

5 (10.2 %)

 •Health care worker

1 (2.1 %)

 •Malignancy

1 (2.1 %)

  1. aOther systemic involvements: bone (n = 1); renal (n = 1)