Table 1 Review of additional reported cases of endogenous endopthalmitis caused by S. apiospermum not reviewed by Larocco et al.
Author | Year | Gender | Age | Comorbidities | Laterality | Culture source | Treatment | Other sites of infection | Outcome |
|---|---|---|---|---|---|---|---|---|---|
McKelvie et al. [9] | 2001 | F | 38 | AML, neutropenia | OU | Blood and vitreous | Intraocular AmpB, Foscarnet, Vanco (dx species postmortem) | Blood | CF |
Figueroa et al. [13] | 2004 | M | 44 | Post-kidney transplant; on mycophenolate, tacrolimus, and corticosteroids | OS | Vitreous | Vitrectomy, PO Vori | None | CF |
Larocco et al. [12] | 2005 | F | 28 | Presumed sinusitis, sepsis 2/2, pseudomemebranous colitis | OD | Vitreous | AmpB IVT and systemic, followed by itraconazole when dx of S. apiospermum was made | None | Evisceration |
Musk et al. [4] | 2006 | M | 57 | Lung transplant due to alpha1-anti-trypsin deficiency, on cyclosporine, azothioprine, and prednisolone | OS | Vitreous and epididymis | PO, IVT, and topical Vori | Lung and skin nodules, epididymoorchitis | Poor vision, remains on voriconozole with no evidence of disease |
M | 63 | Lung transplant for interstitial pneumonitis on high-dose steroids | OS | PCR retinal biopsy, vitreous culture | Intravitreous Vori and AmpB; PO Vori | Kidney, urine | No recovery of vision, survived | ||
Jain et al. [17] | 2007 | F | 59 | Pre-B cell acute LL, neutropenia | OS | Vitreous | Vori IVT and PO | Blood and lung | Enucleation, death from sepsis; NLP |
F | 37 | Pre-B cell acute LL | OS | Vitreous | IVT voriconozole, AmpB | Lung | Endopthalmitis stabilized; multiorgan system failure | ||
F | 21 | Wegener’s granulomatosis; corticosteroids and cyclophosphamide | OU | Vitreous | IVT AmpB, itraconazole | None | No visual recovery, CNS involvement | ||
Chen et al. [7] | 2007 | M | 56 | Post-lung transplant; immunosuppresive Rx | OS | Vitreous | Vitrectomy, IV and IVT Vori | None | Enucleation; secondary scleritis; LP |
M | 62 | Post-lung transplant | OS | Vitreous | PO Vori, IV AmpB, PO terbinafine, IVT Vori | None | Enucleation; LP | ||
Shankar et al. [5] | 2007 | M | 61 | DM, HTN | OD | Aqueous aspirate | Anterior chamber wash and IVT Vori | None | Resolution of vitreous exudates |
Ikewaki et al. [11] | 2009 | M | 58 | DM; sub-Tenon’s triamcinolone injection | OS | Vitreous | Topical and IVT irrigation with Vori | None | Improvement to baselineImprovement to baseline (0.02 to 0.5) |
Present case | 2011 | M | 83 | DM | OD | Vitreous | IV and IVT Vori | None | Stable at 20/40 |