Skip to main content

Table 1 Patient's demographics, clinical details, and previous treatments

From: A retrospective review of oral low-dose sirolimus (rapamycin) for the treatment of active uveitis

Case

Age

Sex

History

Diagnosis

Previous therapy

Reason for sirolimus

1

67

M

Panuveitis OU with CME OD > OS treated with topical steroids.

Sarcoidosis

Topical ketorolac, topical prednisolone

Patient wanted to avoid oral prednisone

2

39

M

Bilateral recurrent anterior uveitis and scleritis treated with multiple orbital floor steroid injections.

Sarcoidosis

Subtenon triamcinolone, oral prednisone

Frequent flares

3

31

F

Chronic anterior uveitis with CME OD previously treated with prednisone and methotrexate. Poor control of inflammation with frequent flares.

Idiopathic

Subtenon triamcinolone, oral prednisone, oral methotrexate

Uncontrolled inflammation with previous regimen

4

26

M

Bilateral chronic intermediate uveitis. Treated for Lyme disease by infectious diseases.

Secondary to Lyme disease

Oral prednisone, oral methotrexate

Uncontrolled inflammation with previous regimen

5

54

M

Granulomatous anterior uveitis with vasculitis and choroidal infiltrates OD s/p repair of ruptured globe and eventual enucleation OS.

Sympathetic ophthalmia

IV methylprednisolone, oral prednisone

Uncontrolled inflammation despite maximal dose of oral prednisone

6

61

M

Panuveitis OU treated with orbital floor steroid injections and high-dose oral corticosteroids. History of hepatitis C and aseptic meningitis.

Sarcoidosis

Subtenon triamcinolone, oral prednisone

Avoid higher doses of oral prednisone

7

79

F

Panuveitis with CME OD > OS treated with oral corticosteroids. History of chronic anemia.

Idiopathic

Oral prednisone

Avoid higher doses of oral prednisone

8

21

M

Recurrent panuveitis treated with high doses of oral corticosteroids.

HLA B27 positive

Oral prednisone

Uncontrolled inflammation despite maximal dose of oral prednisone

  1. F female, M male