Table 1 Systemic manifestations of VEXAS syndrome in a case of a 76-year-old man
From: Recurrent superior orbital fissure syndrome associated with VEXAS syndrome
Organ system | Symptoms |
|---|---|
Respiratory | Recurrent chest infections Pleural effusions Pulmonary hypertension |
Cardiovascular | Heart failure with preserved ejection fraction |
Haematological | Bilateral pulmonary emboli Saphenous vein occlusion Iron deficiency anemia |
Renal | Hyponatremia Microalbuminuria |
Skin | Widespread erythematous plaques Leucocytoclastic vasculitis |
Musculoskeletal | Muscle wasting Globally stiff movements around the spine and hips |
Other | Fatigue Weight loss |