Fig. 1

Multimodal imaging in a 51-year-old female with acute pseudo-Vogt-Koyanagi-Harada (VKH) following one month treatment with a combination of ipilimumab/nivolumab (CTLA-4 and PD-1 checkpoint blockade inhibitors) for a malignant melanoma of the skin. A The fundus photograph of the left eyes reveals multiple deep yellow choroidal lesions with areas of the subretinal detachments in the peripapillary region. B Note multiple hyperfluorescent retinal pigment epithelium leaks on fluorescein angiography with hyperfluorescent dye pooling beneath subretinal fluid. C Optical coherence tomography (OCT) in pseudo-VKH showed a multilobular serous macular detachments, with subretinal hyper-reflective material within the subretinal fluid that likely represents fibrin and a part of the outer segment layer