From: Cytomegalovirus as a cause of hypertensive anterior uveitis in immunocompetent patients
Characteristics | CMV-positive subjects n = 6 | CMV-negative subjects n = 15 | P value |
---|---|---|---|
Demographic characteristics | |||
Male, n (%) | 6 (100 %) | 13 (86.7 %) | 0.500 |
Age, years | 47.5 ± 14.8 | 67.6 ± 11.8 | 0.006 |
Ocular characteristics | |||
Initial BCVA | 0.65 ± 0.29 | 0.58 ± 0.29 | 0.569 |
Final BCVA | 0.47 ± 0.46 | 0.52 ± 0.30 | 0.733 |
Spherical equivalent, D | -3.6 ± 4.2 | 0.0 ± 1.6 | 0.031 |
Axial length, mm | 25.7 ± 1.5 | 24.4 ± 0.7 | 0.053 |
Glaucoma, n (%) | 6 (100 %) | 13 (86.7 %) | 0.347 |
Average RNFL thickness, μm | 66.2 ± 16.7 | 77.8 ± 19.1 | 0.132 |
Corneal endothelial cell count, mm2 | 1245 ± 560 | 1981 ± 387 | 0.009 |
Unilaterality, n (%) | 83.3 | 80.0 | 0.684 |
KPs at baseline examination, n (%) | 83.3 | 73.3 | 0.550 |
Presence of PAS, n (%) | 4 (66.7 %) | 5 (33.3 %) | 0.331 |
Anterior chamber reaction with 1+ or less, n (%) | 100.0 | 92.9 | 0.714 |
Lens status, phakic, n (%) | 5 (83.3 %) | 5 (33.3 %) | 0.055 |
Baseline IOP, mmHg | 28.83 ± 8.25 | 22.73 ± 7.86 | 0.132 |
Maximum IOP, mmHg | 37.17 ± 8.03 | 39.53 ± 13.02 | 0.622 |
Final IOP, mmHg | 13.3 ± 3.44 | 13.5 ± 5.05 | 0.950 |
Number of anti-glaucoma medication, n | 2.67 ± 0.81 | 2.67 ± 0.81 | 0.970 |
Course of uveitis | 0.544 | ||
Chronic, n (%) | 4 (66.7 %) | 13 (86.7 %) | |
Recurrent, n (%) | 2 (33.3 %) | 2 (13.3 %) | |
Glaucoma operation, n (%) | 4 (66.7 %) | 10 (66.7 %) | 0.701 |
Choice of glaucoma operation | 0.095 | ||
Ahmed valve, n (%) | 3 (75.0 %) | 2 (20.0 %) | |
Trabeculectomy or ExPRESSⓡ, n (%) | 1 (25.0 %) | 8 (80.0 %) | |
HSV PCR positivity, n (%) | 0 (0.0 %) | 1 (6.2 %) | 0.727 |
CMV RQ PCR, copies/mL | 46,048.8 ± 91,334.5 | Negative | n/a |